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Dr. Mikhail Tsurkan

Institute of Biofunctional Polymer Materials
+49 351 4658 1265 +49 351 4658 533

Mikhail Tsurkan PhD is the leader of the spin-off project TissueGUARD. The project TissueGUARD is part of the EXIST program and is funded by the German Federal Ministry for Economic Affairs and Energy (BMWi) and the European Social Fund (ESF) as well as the Leibniz Institute of Polymer Research Dresden (IPF) Germany.

Fields of work

The research is focused on the development of new Biofunctional Materials for the needs of regenerative therapies and stem cell research which includes:

  • Design and synthesis of peptide and carbohydrate conjugates for biomedical and biomaterial applications
  • Incorporation of biological active molecules into hydrogel materials through rational synthesis
  • Photochemical and photophysical developments for biofunctional materials applications
  • Development of bioanalytical methods for natural compounds and biopolymers characterization

Additional information

Publications

  • Pokharkar, O. ; Lakshmanan, H. ; Zyryanov, G. ; Tsurkan, M. In silico evaluation of antifungal compounds from marine sponges against COVID-19-associated mucormycosis more Marine Drugs 20 (2022) 215
  • Kovalev, I. ; Taniya, O.S. ; Sadieva , L. K. ; Volkova, N.N. ; Minin , A. S. ; Grzhegorzhevskii, K. V. ; Gorbunov, E. B. ; Zyryanov, G. ; Chupakhin, O. ; Charushin , V. N. ; Tsurkan, M. Bola-type PAH-based fluorophores/chemosensors: Synthesis via an unusual clemmensen reduction and photophysical studies more Journal of Photochemistry and Photobiology A: Chemistry 420 (2021) 113466
  • Kovalev, I. ; Sadieva , L. K. ; Taniya, O.S. ; Yurk , V. M. ; Minin , A. S. ; Santra, S. ; Zyryanov, G. ; Charushin , V. N. ; Chupakhin, O. ; Tsurkan, M. Computer vision vs. spectrofluorometer-assisted detection of common nitro-explosive components with bola-type PAH-based chemosensors more RSC Advances 11 (2021) 25850-25857
  • Lee, Y. ; Bandari, V. K. ; Li, Z. ; Medina-Sánchez, M. ; Maitz, M.F. ; Karnaushenko, D. ; Tsurkan, M. ; Karnaushenko, D. D. ; Schmidt, O. G. Nano-biosupercapacitors enable autarkic sensor operation in blood more Nature Communications 12 (2021) 4967
  • Satish, L. ; Santra, S. ; Tsurkan, M. ; Werner, C. ; Jana, M. ; Sahoo, H. Conformational changes of GDNF-derived peptide induced by heparin, heparan sulfate, and sulfated hyaluronic acid - Analysis by circular dichroism spectroscopy and molecular dynamics simulation more International Journal of Biological Macromolecules 182 (2021) 2144-2150
  • Jaeschke, A. ; Harvey, N.R. ; Tsurkan, M. ; Werner, C. ; Griffiths, L.R. ; Haupt, L.M. ; Bray, L. Techniques for RNA extraction from cells cultured in starPEG-heparin hydrogels more Open Biology 11 (2021) 200388
  • Tsurkan, M. ; Voronkina, A. ; Khrunyk, Y.Y. ; Wysokowski, M. ; Petrenko, I. ; Ehrlich, H. Progress in chitin analytics more Carbohydrate Polymers 252 (2021) 117204
  • Talevski, T. ; Leshoska, A.T. ; Pejoski, E. ; Pejin, B. ; Machalowski, T. ; Wysokowski, M. ; Tsurkan, M. ; Petrova, O. V. ; Sivkov, V. N. ; Martinovic, R. ; Pantovic, S. ; Khrunyk, Y.Y. ; Trylis, V. ; Fursov, A. ; Djurovic, M. ; Jesionowski, T. ; Ehrlich, Identification and first insights into the structure of chitin from the endemic freshwater demosponge Ochridaspongia rotunda (Arndt, 1937) more International Journal of Biological Macromolecules 162 (2020) 1187-1194
  • Koch, K.M. ; Jaeschke, A. ; Murekatete, B. ; Ravichandran, A. ; Tsurkan, M. ; Werner, C. ; Soon, P. ; Hutmacher, D. W. ; Haupt, L.M. ; Bray, L. Stromal fibroblasts regulate microvascular-like network architecture in a bioengineered breast tumour angiogenesis model more Acta Biomaterialia 114 (2020) 256-269
  • Götze, J. ; Hofmann, B. ; Machalowski, T. ; Tsurkan, M. ; Jesionowski, T. ; Ehrlich, H. ; Kleeberg, R. ; Ottens, B. Biosignatures in subsurface filamentous fabrics (SFF) from the Deccan Volcanic Province, India more Minerals 10 (2020) 540
  • Nowacki, K. ; Stepniak, I. ; Langer, E. ; Tsurkan, M. ; Wysokowski, M. ; Petrenko, I. ; Khrunyk, Y.Y. ; Fursov, A. ; Bo, M. ; Bavestrello, G. ; Joseph, Y. ; Ehrlich, H. Electrochemical approach for isolation of chitin from the skeleton of the black coral. Cirrhipathes sp. (Antipatharia) more Marine Drugs 18 (2020) 297
  • Binnewerg, B. ; Schubert, M. ; Voronkina, A. ; Muzychka , L. ; Petrenko, I. ; Djurovic, M. ; Kovalchuk, V. ; Tsurkan, M. ; Bechmann, N. ; Fursov, A. ; Ivanenko, V.N. ; Smolii , O.B. ; Joseph, Y. ; Giovine, M. ; Bornstein, S. R. ; Stelling, A. ; Tunger, A Marine biomaterials: Biomimetic and pharmacological potential of cultivated Aplysina aerophoba marine demosponge more Materials Science and Engineering C - Materials for Biological Applications 109 (2020) 110566
  • Khrunyk, Y.Y. ; Belikov, S. ; Tsurkan, M. ; Vyalykh, I.V. ; Markaryan, A.Y. ; Karabanalov, M.S. ; Popov, A. A. ; Wysokowski, M. Surface-dependent osteoblasts response to TiO2 nanotubes of different crystallinity more Nanomaterials 10 (2020) 320
  • Schirmer, L. ; Chwalek, K. ; Tsurkan, M. ; Freudenberg, U. ; Werner, C. Glycosaminoglycan-based hydrogels with programmable host reactions more Biomaterials 228 (2020) 119557
  • Husman, D. ; Welzel, P. ; Vogler, S. ; Bray, L. ; Träber, N. ; Friedrichs, J. ; Körber, V. ; Tsurkan, M. ; Freudenberg, U. ; Thiele, J. ; Werner, C. Multiphasic microgel-in-gel materials to recapitulate cellular mesoevironments in vitro more Biomaterials Science 2020 (2020) 101-108
  • Machalowski, T. ; Wysokowski, M. ; Zoltowska-Aksamitowska, S. ; Tsurkan, M. ; et al., Spider Chitin. The biomimetic potential and applications of Caribena versicolor tubular chitin more Carbohydrate Polymers 226 (2019) 115301
  • Schubert, M. ; Binnewerg, B. ; Voronkina, A. ; ..., ; Tsurkan, M. ; et al., Naturally prefabricated marine biomaterials: Isolation and applications of flat chitinous 3D scaffolds from Ianthella labyrinthus (Demospongiae: Verongiida) more International Journal of Molecular Sciences 20 (2019) 5105
  • Kovalchuk, V. ; Voronkina, A. ; Binnewerg, B. ; Tsurkan, M. ; et al., Naturally drug-loaded chitin: Isolation and applications more Marine Drugs 17 (2019) 574
  • Brierly, G.I. ; Ren, J. ; Baldwin, J. ; Saifzadeh, S. ; Theodoropoulos, C. ; Tsurkan, M. ; Lynham, A. ; Hsu, E. ; Nikolarakos, D. ; Werner, C. ; Woodruff, M.A. ; Hutmacher, D. W. ; Bray, L. Investigation of sustained BMP delivery in the prevention of medication-related osteonecrosis of the jaw (MRONJ) in a rat model more Macromolecular Bioscience 19 (2019) 1900226
  • Machalowski, T. ; Wysokowski, M. ; Tsurkan, M. ; et al., Spider Chitin: An ultrafast microwave-assisted method for chitin isolation from caribena versicolor spider molt cuticle more Molecules 24 (2019) 3736
  • Rahman, M. ; Mukherjee, A. ; Kovalev, I. ; Kopchuk, D. ; Zyryanov, G. ; Tsurkan, M. ; Majee, A. ; Ranu, B. ; Charishin, V.N. ; Chupakhin, O. ; Santra, S. Recent advances on diverse decarboxylative reactions of amino acids more Advanced Synthesis & Catalysis 361 (2019) 2161-2214
  • Klinger, Ch. ; Zoltowska-Aksamitowska, S. ; Wysokowski, M. ; Tsurkan, M. ; Galli, R. ; et al., Express method for isolation of ready-to-use 3D chitin scaffolds from aplysina archeri (aplysineidae: verongiida) demosponge more Marine Drugs 17 (2019) ID 131
  • Shaala, L. A. ; Asfour, H.Z. ; Youssef, D.T.A. ; Zoltowska-Aksamitowska, S. ; Wysokowski, M. ; Tsurkan, M. ; et al., New source of 3D chitin scaffolds: The red sea demosponge pseudoceratina arabica (pseudoceratinidae, verongiida) more Marine Drugs 17 (2019) ID 92
  • Atallah, P. ; Schirmer, L. ; Tsurkan, M. ; Limasale, Y. D. P. ; Zimmermann, R. ; Werner, C. ; Freudenberg, U. In situ-forming, cell-instructive hydrogels based on glycosaminoglycans with varied sulfation patterns more Biomaterials 181 (2018) 227-239
  • Zóltowska-Aksamitowska, S. ; Tsurkan, M. ; Lim, S. C. ; et al., The demosponge Pseudoceratina purpurea as a new source of fibrous chitin more International Journal of Biological Macromolecules 112 (2018) 1021-1028