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Authors
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Burkert, S. ; Gohs, U. ; Uhlmann, P. ; Stamm, M.
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Title
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Tuning of biocompatible thermo-sensitive polymer brushes by e-beam irradiation
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Date
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28.08.2009
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Number
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19293
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Abstract
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Polymer brushes can be used to control adsorption mechanism e.g. protein adsorption. Those tethered polymer chains are sensitive to various factors like pH value, solvent or temperature. In combination with a second polymer mixed brushes are created which can switch their surface properties and therefore influence adsorption mechanisms of e.g. proteins. Focusing on temperature as external stimulus we chose PS-PNIPAAM mixed brushes to regulate the protein adsorption, where PNIPAAM deswells above its LCST of 32 °C. The PS brush, however, does not change. In a second approach we extend the control of surface modification by applying a dose gradient via electron irradiation. This technique enables additional local control of modification especially when generating a gradient or structures in the brush layer.
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Publisher
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Polymeric Materials: Science and Engineering
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Wikidata
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Citation
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Polymeric Materials: Science and Engineering 101 (2009) 1162
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DOI
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http://oasys2.confex.com/acs/238nm/techprogram/P1277534.HTM
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