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Authors
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Ionov, L. ; Stamm, M. ; Diez, S.
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Title
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Size sorting of protein assemblies using polymeric gradient surfaces
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Date
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31.12.2005
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Number
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15203
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Abstract
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We report on a novel approach for the size-dependent fractionation of protein assemblies on polymeric surfaces. Using a simple temperature gradient method to generate one-dimensional gradients of grafted poly(ethylene glycol), we fabricated silicon-oxide chips with a gradually changing surface density of kinesin motor molecules. We demonstrate that such a bioactive surface can be used to sort gliding microtubules according to their length. To our knowledge, this is the first example of the self-organized sorting of protein assemblies on surfaces.
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Publisher
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Nano letters
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Wikidata
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Citation
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Nano letters 5 (2005) 1910-1914
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DOI
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https://doi.org/10.1021/nl051235h
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Tags
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kinesin density fabrication adsorption molecules behavior brushes motors layers
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