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Dr. Manfred Maitz

Institute of Biofunctional Polymer Materials
+49 351 4658 606/ 313 +49 351 4658 533

Personal Data

Manfred Maitz is responsible for the field of hemocompatible surfaces in the Institute Biofunctional Polymer Materials. He is a medical doctor (Dr. med.) by education and has been working on biomaterials research in institutes in Würzburg, Ulm, Magdeburg, Dresden and Chengdu (PR China) before he joined the IPF in 2006.

He is Guest Professor at Southwest Jiaotong University, School of Materials Science and Engineering in Chengdu, China, where he has annual research stays as guest scientist.

His focus of research is on feedback responsive materials to control blood coagulation and inflammatory responses at biomaterials in blood. These are important as vascular stents, artificial heart valves, hemodialysis membranes or tubings for extracorporeal circulation, etc.

He is member of the WTR in the IPF.

 Research experiences

2006 – presentResearch Fellow and Group Leader, Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, Germany
2005Foreign Expert scientist, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China
2000 – 2004Thematic field leader, Research Center Rossendorf, Institute of Ion Beam Physics and Materials Research, Dresden, Germany
1999Assistant, Institute for Pathology, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany
1998Research Fellow, Central Institute of Biomedical Techniques, University of Ulm, Ulm, Germany

 Membership of Academic Societies


Key Publications

  1. Maitz M.F., Zitzmann J., Hanke J., Renneberg C., Tsurkan M.V., Sperling C., Freudenberg U., Werner C. Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors. Biomaterials 135: 53-61 (2017). doi:10.1016/j.biomaterials.2017.04.044
  2. Herklotz M., Hanke J., Hänsel S., Drichel J., Marx M., Maitz M.F., Werner C. Biomaterials trigger endothelial cell activation in co-incubation with human whole blood. Biomaterials 104: 258-268 (2016). doi:10.1016/j.biomaterials.2016.07.022
  3. Maitz M.F. Applications of synthetic polymers in clinical medicine. Biosurf Biotribol 1(3): 161-176 (2015). doi:10.1016/j.bsbt.2015.08.002
  4. M.F., Freudenberg U., Tsurkan M.V., Fischer M., Beyrich T., Werner C. Bio-responsive polymer hydrogels homeostatically regulate blood coagulation. Nature Commun (2013). doi:10.1038/ncomms3168
  5. Sperling C., Fischer M., Maitz M.F., Werner C. Blood coagulation on biomaterials requires the combination of distinct activation processes. Biomaterials 30(27): 4447-4456 (2009). doi:10.1016/j.biomaterials.2009.05.044
  6. Werner C., Maitz M.F., Sperling C. Current strategies towards hemocompatible coatings. J Mater Chem 17: 3376-3384 (2007). doi:10.1039/b703416b



  • Helmecke, T.; Rose, I. I.; Tsurkan, M. V.; Roth, H.; Maitz, M. F.; Werner, C.; Wessling, M. Poly(styrene-alt-maleic anhydride)-copolymers blended in poly(ether sulfone) membranes as a platform for effective biomolecular surface functionalization more Journal of Membrane Science 689 (2024) 122050
  • Valtin, J.; Behrens, S.; Ruland, A.; Schmieder, F.; Sonntag, F.; Renner, L. D.; Maitz, M. F.; Werner, C. A New In Vitro Blood Flow Model for the Realistic Evaluation of Antimicrobial Surfaces more Advanced Healthcare Materials 12 (2023) 2301300
  • Sperling, C.; Maitz, M. F.; Körber, V.; Hänsel, S.; Werner, C. Advanced in vitro hemocompatibility assessment of biomaterials using a new flow incubation system more Biomaterials Advances 153 (2023) 213555
  • Han, X.; Lu, B.; Zou, D.; Luo, X.; Liu, L.; Maitz, M. F.; Yang, P.; Huang, N.; Zhao, A.; Chen, J. Allicin-Loaded Intelligent Hydrogel Coating Improving Vascular Implant Performance more ACS Applied Materials & Interfaces 15 (2023) 38247–38263
  • Peng, Y.-H.; Hsiao, S. K.; Gupta, K.; Ruland, A.; Auernhammer, G. K.; Maitz, M. F.; Boye, S.; Lattner, J.; Gerri, C.; Honigmann, A.; Werner, C.; Krieg, E. Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture more Nature Nanotechnology (2023) - Early Access
  • Schimper, C. B.; Pachschwöll, P.; Maitz, M. F.; Werner, C.; Rosenau, T.; Liebner, F. Hemocompatibility of cellulose phosphate aerogel membranes with potential use in bone tissue engineering more Frontiers in Bioengineering and Biotechnology 11 (2023) 1152577
  • Dittfeld, C. ; Welzel, C. ; König, U. ; Jannasch, A. ; Alexiou, K. ; Blum, E. ; Bronder, S. ; Sperling, C. ; Maitz, M.F. ; Tugtekin, S.-M. Hemocompatibility tuning of an innovative glutaraldehyde-free preparation strategy using riboflavin/UV crosslinking and electron irradiation of bovine pericardium for cardiac substitutes more Biomaterials Advances 147 (2023) 213328
  • Helmecke, T. ; Hahn, D. ; Matzke, N. ; Ferdinand, L. ; Franke, L. ; Kühn, S. ; Fischer, G. ; Werner, C. ; Maitz, M.F. Inflammation-controlled anti-inflammatory hydrogels more Advanced Science 10 (2023) 2206412
  • Dou, Z. ; Chen, S. ; Wang, J. ; Xia, L. ; Maitz, M.F. ; Tu, Q. ; Zhang, W. ; Yang, Z. ; Huang, N. A "built-up" composite film with synergistic functionalities on Mg-2Zn-1Mn bioresorbable stents improves corrosion control effects and biocompatibility more Bioactive Materials 25 (2023) 223-238
  • Zhou, L. ; Zhang, L. ; Li, P. ; Maitz, M.F. ; Wang, K. ; Shang, T. ; Dai, S. ; Fu, Y. ; Zhao, Y. ; Yang, Z. ; Wang, J. ; Li, X. Adhesive and self-healing polyurethanes with tunable multifunctionality more Research: Official Journal of CAST 2022 (2022) 9795682
  • Lu, B. ; Han, X. ; Zou, D. ; Luo, X. ; Liu, L. ; Wang, J. ; Maitz, M.F. ; Yang, P. ; Huang, N. ; Zhao, A.S. Catechol-chitosan/polyacrylamide hydrogel wound dressing for regulating local inflammation more Materials Today Bio 16 (2022) Article Number: 100392
  • Zhou, Z. ; Luo, R. ; Chen, L. ; Hu, C. ; Chen, C. ; Maitz, M.F. ; Li, L. ; Yang, L. ; Deng, D. ; An, Y. ; Wu, H. ; Yang, Y. ; Dai, Y. ; Xin, J. ; Wang, Y. Dressing blood-contacting devices with platelet membrane enables large-scale multifunctional biointerfacing more Matter 5 (2022) 2334-2351
  • Bockholt, R. ; Paschke, S. ; Heubner, L. ; Ibarlucea, B. ; Laupp, A. ; Janicijevic, Z. ; Klinghammer, S. ; Balakin, S. ; Maitz, M.F. ; Werner, C. ; Cuniberti, G. ; Baraban, L. ; Spieth, P.M. Real-time monitoring of blood parameters in the intensive care unit: state-of-the-art and perspectives more Journal of Clinical Medicine 11 (2022) 2408
  • Wang, Y. ; Wu, H. ; Zhou, Z. ; Maitz, M.F. ; Liu, K. ; Zhang, B. ; Yang, L. ; Luo, R. ; Wang, Y. A thrombin-triggered self-regulating anticoagulant strategy combined with anti-inflammatory capacity for blood-contacting implants more Science Advances 8 (2022) abm3378
  • Chen, L. ; Zhou, Z. ; Hu, C. ; Maitz, M.F. ; Yang, L. ; Luo, R. ; Wang, Y. Platelet membrane-coated nanocarriers targeting plaques to deliver anti-CD47 antibody for atherosclerotic therapy more Research: Official Journal of CAST 2022 (2022) 9845459
  • Shao, Z. ; Jiang, X. ; Li, F. ; Zhu, M. ; Maitz, M.F. ; Song, T. Construction of corrosion resistant and osteogenic multiphase reinforced Titanium/hydroxyapatite nanocomposites prepared by spark plasma sintering more Composite Interfaces 29 (2022) 853-876
  • Ma, Q. ; Shi, X. ; Tan, X. ; Wang, R. ; Xiong, K. ; Maitz, M.F. ; Cui, Y. ; Hu, Z. ; Tu, Q. ; Huang, N. ; Shen, L. ; Yang, Z. Durable endothelium-mimicking coating for surface bioengineering cardiovascular stents more Bioactive Materials 6 (2021) 4786-4800
  • Dittfeld, C. ; König, U. ; Welzel, C. ; Jannasch, A. ; Matschke, K. ; Sperling, C. ; Tugtekin, S.-M. ; Maitz, M.F. Haemocompatibility testing allows selective adaption of GA-free SULEEI-preparation strategy for bovine pericardium more European Heart Journal 42 (2021) 3336-3336
  • Hahn, D. ; Sonntag, J. M. ; Lück, S. ; Maitz, M.F. ; Freudenberg, U. ; Jordan, R. ; Werner, C. Poly(2-alkyl-2-oxazoline)-heparin hydrogels - expanding the physicochemical parameter space of biohybrid materials more Advanced Healthcare Materials 10 (2021) 2101327
  • Valtin, J. ; Behrens , S. ; Maitz, M.F. ; Schmieder, F. ; Sonntag, F. ; Werner, C. A modular in vitro flow model to analyse blood-surface interactions under physiological conditions more Current Directions in Biomedical Engineering 7 (2021) 171-174
  • Zhang, B. ; Yao, R. ; Maitz, M.F. ; Mao, G. ; Hou, Z. ; Hu, H. ; Luo, R. ; Wang, Y. Poly (dimethyl diallyl ammonium chloride) incorporated multilayer coating on biodegradable AZ31 magnesium alloy with enhanced resistance to chloride corrosion and promoted endothelialization more Chemical Engineering Journal 421, Part 2 (2021) 127724
  • Gorenkova, N. ; Maitz, M.F. ; Böhme, G. ; Alhadrami, H. A. ; Jiffri, E. H. ; Totten , J. D. ; Werner, C. ; Carswell, H.V.O. ; Seib, F. P. The innate immune response of self-assembling silk fibroin hydrogels more Biomaterials Science 9 (2021) 7194-7204
  • Lee, Y. ; Bandari, V. K. ; Li, Z. ; Medina-Sánchez, M. ; Maitz, M.F. ; Karnaushenko, D. ; Tsurkan, M. ; Karnaushenko, D. D. ; Schmidt, O. G. Nano-biosupercapacitors enable autarkic sensor operation in blood more Nature Communications 12 (2021) 4967
  • Wang, X. ; Xu, K. ; Cui, W. ; Yang, X. ; Maitz, M.F. ; Li, W. ; Li, X. ; Chen, J. Controlled synthesis of mussel-inspired Ag nanoparticle coatings with demonstrated in vitro and in vivo antibacterial properties more Materials & Design 208 (2021) 109944
  • Johnbosco, C. ; Zschoche, St. ; Nitschke, M. ; Hahn, D. ; Werner, C. ; Maitz, M.F. Bioresponsive starPEG-heparin hydrogel coatings on vascular stents for enhanced hemocompatibility more Materials Science and Engineering: C 128 (2021) 112268