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Dr. Manfred Maitz

Institute of Biofunctional Polymer Materials
+49 351 4658 606/ 313 +49 351 4658 533

Personal Data

Manfred Maitz is responsible for the field of hemocompatible surfaces in the Institute Biofunctional Polymer Materials. He is a medical doctor (Dr. med.) by education and has been working on biomaterials research in institutes in Würzburg, Ulm, Magdeburg, Dresden and Chengdu (PR China) before he joined the IPF in 2006.

He is Guest Professor at Southwest Jiaotong University, School of Materials Science and Engineering in Chengdu, China, where he has annual research stays as guest scientist.

His focus of research is on feedback responsive materials to control blood coagulation and inflammatory responses at biomaterials in blood. These are important as vascular stents, artificial heart valves, hemodialysis membranes or tubings for extracorporeal circulation, etc.

He is member of the WTR in the IPF.

 Research experiences

2006 – presentResearch Fellow and Group Leader, Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, Germany
2005Foreign Expert scientist, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China
2000 – 2004Thematic field leader, Research Center Rossendorf, Institute of Ion Beam Physics and Materials Research, Dresden, Germany
1999Assistant, Institute for Pathology, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany
1998Research Fellow, Central Institute of Biomedical Techniques, University of Ulm, Ulm, Germany

 Membership of Academic Societies

Profiles

Key Publications

  1. Maitz M.F., Zitzmann J., Hanke J., Renneberg C., Tsurkan M.V., Sperling C., Freudenberg U., Werner C. Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors. Biomaterials 135: 53-61 (2017). doi:10.1016/j.biomaterials.2017.04.044
  2. Herklotz M., Hanke J., Hänsel S., Drichel J., Marx M., Maitz M.F., Werner C. Biomaterials trigger endothelial cell activation in co-incubation with human whole blood. Biomaterials 104: 258-268 (2016). doi:10.1016/j.biomaterials.2016.07.022
  3. Maitz M.F. Applications of synthetic polymers in clinical medicine. Biosurf Biotribol 1(3): 161-176 (2015). doi:10.1016/j.bsbt.2015.08.002
  4. http://dx.doi.org/10.1016/j.bsbt.2015.08.002Maitz M.F., Freudenberg U., Tsurkan M.V., Fischer M., Beyrich T., Werner C. Bio-responsive polymer hydrogels homeostatically regulate blood coagulation. Nature Commun (2013). doi:10.1038/ncomms3168
  5. Sperling C., Fischer M., Maitz M.F., Werner C. Blood coagulation on biomaterials requires the combination of distinct activation processes. Biomaterials 30(27): 4447-4456 (2009). doi:10.1016/j.biomaterials.2009.05.044
  6. Werner C., Maitz M.F., Sperling C. Current strategies towards hemocompatible coatings. J Mater Chem 17: 3376-3384 (2007). doi:10.1039/b703416b

 

Publications

  • Ma, Q. ; Shi, X. ; Tan, X. ; Wang, R. ; Xiong, K. ; Maitz, M.F. ; Cui, Y. ; Hu, Z. ; Tu, Q. ; Huang, N. ; Shen, L. ; Yang, Z. Durable endothelium-mimicking coating for surface bioengineering cardiovascular stents more Bioactive Materials 6 (2021) 4786-4800
  • Hahn, D. ; Sonntag, J. M. ; Lück, S. ; Maitz, M.F. ; Freudenberg, U. ; Jordan, R. ; Werner, C. Poly(2-alkyl-2-oxazoline)-heparin hydrogels - expanding the physicochemical parameter space of biohybrid materials more Advanced Healthcare Materials 2101327 (2021) Early view
  • Gorenkova, N. ; Maitz, M.F. ; Böhme, G. ; Alhadrami, H. A. ; Jiffri, E. H. ; Totten , J. D. ; Werner, C. ; Carswell, H.V.O. ; Seib, F. P. The innate immune response of self-assembling silk fibroin hydrogels more Biomaterials Science (2021) Advance Article
  • Lee, Y. ; Bandari, V. K. ; Li, Z. ; Medina-Sánchez, M. ; Maitz, M.F. ; Karnaushenko, D. ; Tsurkan, M. ; Karnaushenko, D. D. ; Schmidt, O. G. Nano-biosupercapacitors enable autarkic sensor operation in blood more Nature Communications 12 (2021) 4967
  • Wang, X. ; Xu, K. ; Cui, W. ; Yang, X. ; Maitz, M.F. ; Li, W. ; Li, X. ; Chen, J. Controlled synthesis of mussel-inspired Ag nanoparticle coatings with demonstrated in vitro and in vivo antibacterial properties more Materials & Design 208 (2021) 109944
  • Johnbosco, C. ; Zschoche, St. ; Nitschke, M. ; Hahn, D. ; Werner, C. ; Maitz, M.F. Bioresponsive starPEG-heparin hydrogel coatings on vascular stents for enhanced hemocompatibility more Materials Science and Engineering: C 128 (2021) 112268
  • Yu, H. ; Qiu, H. ; Man, W. ; Maitz, M.F. ; Tu, Q. ; Xiong, K. ; Chen, J. ; Huang, N. ; Yang, Z. Endothelium-mimicking surface combats thrombosis and biofouling via synergistic long- and short-distance defense strategy more Small 17 (2021) 2100729
  • Wang, X. ; Lu, L. ; Bei, H. P. ; Li, X. ; Du, Z. ; Maitz, M.F. ; Huang, N. ; Tu, Q. ; Zhao, X. ; Yang, Z. Self-protonating, plasma polymerized, superimposed multi-layered biomolecule nanoreservoir as blood-contacting surfaces more Chemical Engineering Journal 410 (2021) 128313
  • Lu, B. ; Han, X. ; Zhao, A. S. ; Luo, D. ; Maitz, M.F. ; Wan, H. ; Yang, P. ; Huang, N. Intelligent H2S release coating for regulating vascular remodeling more Bioactive Materials 6 (2021) 1040-1050
  • Qiu, H. ; Tu, Q. ; Gao, P. ; Li, X. ; Maitz, M.F. ; Xiong, K. ; Yang, Z. Phenolic-amine chemistry mediated synergistic modification with polyphenols and thrombin inhibitor for combating the thrombosis and inflammation of cardiovascular stents more Biomaterials 269 (2021) 120626
  • Zhang, B. ; Yao, R. ; Hu, C. ; Maitz, M.F. ; Wu, H. ; Liu, K. ; Yang, L. ; Luo, R. ; Wang, Y. Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release more Biomaterials (2021) 120418
  • Zhang, B. ; Yao, R. ; Maitz, M.F. ; Mao, G. ; Hou, Z. ; Hu, H. ; Luo, R. ; Wang, Y. Poly (dimethyl diallyl ammonium chloride) incorporated multilayer coating on biodegradable AZ31 magnesium alloy with enhanced resistance to chloride corrosion and promoted endothelialization more Chemical Engineering Journal (2021) article in press, 127724
  • Singh, T. ; Hook, A.L. ; Luckett, J. ; Maitz, M.F. ; Sperling, C. ; Werner, C. ; Davies, M. C. ; Irvine, J.D. ; Williams, P. ; Alexander, M. Discovery of hemocompatible bacterial biofilm-resistant copolymers more Biomaterials 260 (2020) 120312
  • Besford, Q.A. ; Weiss, A.C.G. ; Schubert, J. ; Ryan, T.M. ; Maitz, M.F. ; Tomanin, P.P. ; Savioli, M. ; Werner, C. ; Fery, A. ; Caruso, F. ; Cavalieri, F. Protein component of oyster glycogen nanoparticles: An anchor point for functionalization more ACS Applied Materials & Interfaces 12 (2020) 38976-38988
  • Chen, J. ; Dai, S. ; Liu, L. ; Maitz, M.F. ; Liao, Y. ; Cui, J. ; Zhao, A. S. ; Yang, P. ; Huang, N. ; Wang, Y. Photo-functionalized TiO2 nanotubes decorated with multifunctional Ag nanoparticles for enhanced vascular biocompatibility more Bioactive Materials 6 (2020) 45-54
  • Xiao, Y. ; Wang, W. ; Tian, X. ; Tan, X. ; Yang, T. ; Gao, P. ; Xiong, K. ; Tu, Q. ; Wang, M. ; Maitz, M.F. ; Huang, N. ; Pan, G. ; Yang, Z. A versatile surface bioengineering strategy based on mussel-inspired and bioclickable peptide mimic more Research: Official Journal of CAST (2020) 7236946
  • Yang, Y. ; Gao, P. ; Wang, J. ; Tu, Q. ; Bai, L. ; Xiong, K. ; Qiu, H. ; Zhao, X. ; Maitz, M.F. ; Wang, H. ; Li, X. ; Zhao, Q. ; Xiao, Y. ; Huang, N. ; Yang, Z. Endothelium-mimicking multifunctional coating modified cardiovascular stents via a stepwise metal-catechol-(amine) surface engineering strategy more Research: Official Journal of CAST (2020) 9203906
  • Xu, H. ; Medina-Sanchez, M. ; Maitz, M.F. ; Werner, C. ; Schmidt, O. G. Sperm micromotors for cargo delivery through flowing blood more ACS Nano 14 (2020) 2982-2993
  • Ye, C. ; Wang, J. ; Zhao, A. S. ; He, D. ; Maitz, M.F. ; Zhou, N. ; Huang, N. Atorvastatin eluting coating for magnesium-based stents: Control of degradation and endothelialization in a microfluidic assay and in vivo more Advanced Materials Technologies 5 (2020) 1900947
  • Jopp, S. ; Molenda, R. ; Seiler, E.R.D. ; Maitz, M.F. ; Villinger, A. ; Ehlers, P. ; Langer, P. Total synthesis of dabigatran revisited; Synthesis of amidine-tosylated dabigatran more Chemistry Select 4 (2019) 13802-13805
  • Cordeiro, A. L. ; Rückel, M. ; Bartels, F. ; Maitz, M.F. ; Renner, L. ; Werner, C. Protein adsorption dynamics to polymer surfaces revisited—A multisystems approach more Biointerphases 14 (2019) 051005
  • Sefton, M.V. ; Sperling, C. ; Maitz, M.F. ; Werner, C. The blood compatibility challenge: Editorial introduction more Acta Biomaterialia 94 (2019) 1
  • Gorbet, M. ; Sperling, C. ; Maitz, M.F. ; Siedlecki, C.A. ; Werner, C. ; Sefton, M.V. The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells more Acta Biomaterialia 94 (2019) 25-32
  • Maitz, M.F. ; Martins, C. L. ; Grabow, N. ; Matschegewski, C. ; Huang, N. ; Chaikof, E.L. ; Barbosa, M. A. ; Werner, C. ; Sperling, C. The blood compatibility challenge. Part 4: Surface modification for hemocompatible materials: Passive and active approaches to guide blood-material interactions more Acta Biomaterialia 94 (2019) 33-43
  • Qiu, H. ; Qi, P. ; Liu, J. ; Yang, Y. ; Tan, X. ; Xiao, Y. ; Maitz, M.F. ; Huang, N. ; Yang, Z. Biomimetic engineering endothelium-like coating on cardiovascular stent through heparin and nitric oxide-generating compound synergistic modification strategy more Biomaterials 207 (2019) 10-22