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Title New strategies for developing cardiovascular stent surfaces with novel functions (Review)
Date 02.06.2014
Number 43062
Abstract In this review, the authors summarize the developments in surface modification of cardiovascular materials especially in author's laboratory. The authors focus on three different strategies to construct multifunctional surfaces including coimmobilization of various biomolecules on stent surfaces, stem cell based therapy systems, and a single-molecule multipurpose modification strategy in vascular interventional therapy. The roles of various molecules like heparin, gallic acid, various aptamers, and nitric oxide are highlighted in the new strategies for developing cardiovascular stent surfaces with novel functions including excellent hemocompatibility, inhibiting smooth muscle cells proliferation, and native endothelium regeneration. The success of these multifunctional surfaces provides the tremendous potential in designing the next generation of vascular stents. © 2014 American Vacuum Society
Publisher Biointerphases [Elektronische Ressource]
Identifier
Citation Biointerphases [Elektronische Ressource] 9 (2014) 029017
DOI https://doi.org/10.1116/1.4878719
Authors Qi, P. ; Chen, S. ; Liu, T. ; Chen, J. ; Yang, Z. ; Weng, Y. ; Chen, J. ; Wang, J. ; Maitz, M.F. ; Huang, N.
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