Title Mechanically defined microgels by droplet microfluidics
Date 26.10.2016
Number 51441
Abstract Over the last two decades, droplet-based microfluidics has evolved into a versatile tool for fabricating tailored micrometer-sized hydrogel particles. Combining precise fluid handling down to femtoliter scale with diverse hydrogel precursor design, it allows for excellent control over microgel size and shape, but also functionalization and crosslinking density. Consequently, it is possible to tune physicochemical and mechanical properties such as swelling, degradation, stimuli sensitivity, and elasticity by microfluidic droplet templates. This has led to a recent trend in applying microgels as experimental platform in cell culturing, drug delivery, sensing, and tissue engineering. This article highlights advances in microfluidic droplet formation as templates for microgels with tailored physicochemical properties. Special focus is put on evolving design strategies for the synthesis of mechanically defined microgels, their applications, and methods for mechanical characterization on single-particle level. Special Issue: Microfluidics and Macromolecules
Publisher Macromolecular Chemistry and Physics
Identifier 0
Citation Macromolecular Chemistry and Physics 218 (2016) Art.No. 1600418
Authors Heida, T. ; Neubauer, J. ; Seuss, M. ; Hauck, N. ; Thiele, J. ; Fery, A.

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