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Authors
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Thünemann, A. ; Bienert, R. ; Appelhans, D. ; Voit, B.
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Title
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Core-shell structures of oligosaccharide-functionalized hyperbranched poly(ethylene imines)
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Date
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23.11.2012
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Number
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28448
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Abstract
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Hyperbranched poly(ethylene imine)s (PEIs) functionalized with maltose, maltotriose, and maltoheptaose form distinct core-shell globular nanoparticles as revealed by small-angle X-ray scattering (SAXS). The solution structures are quantified using the Beaucage unified exponential/power-law approach. SAXS results were confirmed with dynamic light scattering (DLS). We found that all PEI structures are completely insensitive to changes of temperature (5 °C < T < 80 °C) and pH (1 < pH < 10). This remarkable stability of a compact spherical polymeric structure makes the modified PEIs promising for a wide range of biomedical applications.
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Publisher
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Macromolecular Chemistry and Physics
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Wikidata
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Citation
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Macromolecular Chemistry and Physics 213 (2012) 2362-2369
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DOI
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https://doi.org/10.1002/macp.201100490
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Tags
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colloids core-shell polymers nanoparticles polyamines small-angle x-ray scattering (saxs) biological-properties light-scattering gene delivery dendrimers nanoparticles complex polyethyleneimine glycodendrimers enhancement polymer
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