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Authors
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Magno, V.; Werner, C.
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Title
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Tissue-derived decellularized materials for biomedical applications
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Date
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17.07.2024
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Number
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0
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Abstract
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Decellularized tissue-derived materials – i.e., biomaterials derived from organs or tissues deprived of their potentially immunogenic cellular components – offer an attractive option for the generation of realistic in vitro tissue and disease models and regenerative therapies. A plethora of decellularization protocols and processing methods make such materials available from numerous tissues and in various formats. This chapter provides an overview of the different forms of tissue-derived decellularized extracellular matrix (dECM) materials for biomedical applications, focusing on innovative dECM-based hydrogels. The chapter concludes with a discussion of the challenges and perspectives of dECM materials concerning standardization and control of physicochemical properties for directing tissue repair and function.
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Publisher
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Springer Nature Switzerland AG
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Wikidata
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Citation
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in: Handbook of the Extracellular Matrix: Biologically-Derived Materials / F. R. Maia, J. M. Oliveira, R. L. Reis (Eds.). Cham: Springer, 2024. 841-873; ISBN: 978-3-031-56362-1
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DOI
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https://doi.org/10.1007/978-3-031-56363-8_42
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Tags
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