Authors
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Daubian, D. ; Gaitzsch, J. ; Meier, W.
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Title
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Synthesis and complex self-assembly of amphiphilic block copolymers with a branched hydrophobic poly(2-oxazoline) into multicompartment micelles, pseudo-vesicles and yolk/shell nanoparticles
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Date
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10.01.2020
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Number
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57964
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Abstract
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We report on the synthesis and self-assembly of poly(ethylene oxide)-block-poly(2-(3-ethylheptyl)-2-oxazoline) (PEO-b-PEHOx), a new amphiphilic diblock copolymer obtained via microwave-assisted polymerization of EHOx using a new nosylated PEO macroinitiator. The kinetics of the polymerization in different solvents was crucial to optimize the synthesis and revealed a controlled, yet fast polymerization of the AB diblock copolymer. Differential scanning calorimetry proved that PEO-b-PEHOx shows glass transition temperatures below room temperature, making it suitable for a wide range of self-assembly methods, especially under mild and solvent-free conditions. Self-assembly of PEO-b-PEHOx was then performed using film rehydration and solvent switch. In both cases, we were able to show the formation of various complex structures (multi-compartment micelles (MCMs), pseudo-vesicles and yolk/shell nanoparticles) by light scattering, TEM and Cryo-TEM. Our results show that PEO-b-PEHOx is a potent new AB diblock copolymer due to its fast synthesis and unique self-assembly behavior.
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Publisher
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Polymer Chemistry
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Wikidata
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Citation
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Polymer Chemistry 11 (2020) 1237-1248
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DOI
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https://doi.org/10.1039/C9PY01559K
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Tags
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