Authors Huang, X. ; Hauptmann, N. ; Appelhans, D. ; Formanek, P. ; Frank, S. ; Kaskel, S. ; Voit, B.
Title Synthesis of hetero-polymer functionalized nanocarriers by combining surface-initiated ATRP and RAFT polymerization
Date 07.12.2012
Number 32569
Abstract Smart nanocarriers are created based on a bi-functional hetero-initiator for RAFT and ATRP technique, bi-functionalizing mesoporous silica nanoparticles with two polymer types. The pH-dependent behavior of PDEAEMA as the gatekeeper polymer is verified by electrokinetic measurements and a controlled release behavior is demonstrated using doxorubicin as the drug.
Publisher Small
Citation Small 8 (2012) 3579.3583
Tags raft atrp nanocarriers mesoporous silica nanoparticles bi-functionalization mesoporous silica nanoparticles transfer radical polymerization responsive controlled-release controlled drug-delivery nanocontainers particles biodistribution therapy system

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