Authors Thünemann, A. ; Bienert, R. ; Appelhans, D. ; Voit, B.
Title Core-shell structures of oligosaccharide-functionalized hyperbranched poly(ethylene imines)
Date 23.11.2012
Number 28448
Abstract Hyperbranched poly(ethylene imine)s (PEIs) functionalized with maltose, maltotriose, and maltoheptaose form distinct core-shell globular nanoparticles as revealed by small-angle X-ray scattering (SAXS). The solution structures are quantified using the Beaucage unified exponential/power-law approach. SAXS results were confirmed with dynamic light scattering (DLS). We found that all PEI structures are completely insensitive to changes of temperature (5 °C < T < 80 °C) and pH (1 < pH < 10). This remarkable stability of a compact spherical polymeric structure makes the modified PEIs promising for a wide range of biomedical applications.
Publisher Macromolecular Chemistry and Physics
Citation Macromolecular Chemistry and Physics 213 (2012) 2362-2369
Tags colloids core-shell polymers nanoparticles polyamines small-angle x-ray scattering (saxs) biological-properties light-scattering gene delivery dendrimers nanoparticles complex polyethyleneimine glycodendrimers enhancement polymer

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