Authors Schmidt, U. ; Zschoche, St. ; Werner, C.
Title Modification of Poly(octadecene-alt-maleic anhydride) Films by Reaction with Functional Amines
Date 25.11.2003
Number 10106
Abstract Thin films of poly(octadecene-<I>alt</I>-maleic anhydride) on top of Si wafers and glass plates were modified by reactions with different functional amines to be used in future studies on the relevance of certain molecular surface properties for the covalent immobilization of proteins. For that aim, a strategy was developed and applied to convert the anhydride moieties of the copolymer by functional amines into side chains bearing hydrophilic groups of acidic (carboxylic acid, sulfonic acid), basic (amines), or neutral (poly(ethylene oxide) (PEO), glucose) character. The modification of the copolymer films was achieved through the two-step formation of a cyclic imide, which was very stable in aqueous solution. Depending on the reactivity of the applied amine, the adjustment of the reaction time was suitable for the preparation of partially converted surfaces of the polymer film. Degrees of modification between 5 and 30% (according to X-ray photoelectron spectroscopy data) were obtained. Annealing the modified polymer films induced efficient back-formation of the anhydride groups. By reaction of the layered polyanhydrides with highly crosslinked diamines, amine-functionalized polymer films were produced that were capable of binding secondary polyanhydride layers. &copy; 2002 Wiley Periodicals, Inc. J Appl Polym Sci 87: 1255-1266, 2003
Publisher Journal of Applied Polymer Science
Citation Journal of Applied Polymer Science 87 (2003) 1255-1266

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