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Dr. Jens Friedrichs

Division of Polymer Biomaterials Science
+49 351 4658 595/ 623 +49 351 4658 533

Personal Data

  • 2005-2009 – PhD at the Biotechnology Center of TU Dresden in the research group of Daniel Müller
  • 2010 – research scientist at the Biotechnology Center of TU Dresden
  • since 2011 – research scientist at Leibniz Institute of Polymer Research Dresden

Fields of Work

  • application of atomic force microscopy (imaging, force spectroscopy) to various fields of research
  • main focus on quantification of mammalian and bacterial cell adhesion using single-cell force spectroscopy (SCFS)
  • development of techniques to increase the throughput of SCFS experiments
  • establishment of an AFM service platform

Publications

  • Arnold, G. ; Schade, E. ; Schneider, Y. ; Friedrichs, J. ; Babick, F. ; Werner, C. ; Rohm, H. Influence of individual phospholipids on the physical properties of oil-based suspensions more Journal of the American Oil Chemists' Society 91 (2014) 71-77
  • Ende, G. ; Poitz, D. ; Augstein, A. ; Wiedemann, E. ; Friedrichs, J. ; Werner, C. ; Strasser, R. H. ; Jellinghaus, S. Involvement of ephrinA1 in TNF-alpha-mediated monocyte adhesion more European Heart Journal 34 (2013) P596, 114
  • Poitz, D. ; Stölzel, F. ; Arabanian, L. ; Friedrichs, J. ; Docheva, D. ; Schieker, M. ; Fierro, F. ; Platzbecker, U. ; Ordemann, R. ; Werner, C. ; Bornhäuser, M. ; Strasser, R. H. ; Ehninger, G. ; Illmer, T. MiR-134-mediated b1 integrin expression and function in mesenchymal stem cells more Biochimica et Biophysica Acta : BBA - Molecular cell research 1833 (2013) 3396-3404
  • Teräväinen, T. P. ; Myllymäki, S. M. ; Friedrichs, J. ; Strohmeyer, N. ; Moyano, J. V. ; Wu, C. ; Matlin, K. S. ; Müller, J. ; Manninen, A. aV integrins are required for mechanotransduction in MDCK epithelial cells more PLoS One [Elektronische Ressource] 8 (2013) e71485
  • Prewitz, M. ; Seib, P. ; Bonin, M. v. ; Friedrichs, J. ; Stißel, A. ; Niehage, C. ; Müller, K. ; Anastassiadis, K. ; Waskow, C. ; Hoflack, B. ; Bornhäuser, M. ; Werner, C. Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments more Nature Methods 10 (2013) 788-794
  • Friedrichs, J. ; Müller, D. J. ; Werner, C. Quantifying cellular adhesion to covalently immobilized extracellular matrix proteins by single-cell force spectroscopy more Humana Press 3rd Editio (2013) 19-37
  • Friedrichs, J. ; Legate, K. R. ; Schubert, R. ; Bharadwaj, M. ; Werner, C. ; Müller, D. J. ; Benoit, M. A practical guide to quantify cell adhesion using single-cell force spectroscopy more Methods : a companion to methods in enzymology 60 (2013) 169-178
  • Arnold, G. ; Schuldt, S. ; Schneider, Y. ; Friedrichs, J. ; Babick, F. ; Werner, C. ; Rohm, H. The impact of lecithin on rheology, sedimentation and particle interactions in oil-based dispersions more Colloids and Surfaces A: Physicochemical and Engineering Aspects 418 (2013) 147-156
  • Schöler, M. ; Föste, H. ; Helbig, M. ; Gottwald, A. ; Friedrichs, J. ; Werner, C. ; Augustin, W. ; Scholl, S. ; Majschak, J. P. Local analysis of cleaning mechanisms in CIP processes more Food and Bioproducts Processing 90 (2012) 858-866
  • Friedrichs, J. ; Zieris, A. ; Prokoph, S. ; Werner, C. Quantifying the effect of covalently immobilized enzymes on biofilm formation by atomic force microscopy-based single-cell force spectroscopy more Macromolecular Rapid Communications 33 (2012) 1453-1458