Biologically inspired polymers can shift the boundaries between living and man-made systems. To make this happen, we implement fundamental biological functions such as recognition, assembly, and adaptation in polymer-based, bioconjugated surfaces and engineered matrices.
Charge and Structure at Bio-Interfaces:
New tools and methods are developed and implemented to analyze and control ionic charge, supramolecular structure and bioadhesion at solid/liquid interfaces.
Blood-material interactions are systematically explored through in vitro, whole blood incubation studies that enable the development of anticoagulant coatings containing various types of natural and synthetic inhibitor molecules.
Reconstituted, biopolymer matrices and modular, biofunctional hydrogels are designed for the exo-genous control of cell fate decisions and tissue formation. The resulting permutations are used in bioartifical stem cell microenvironments and morphogenetic matrices for in vivo tissue engineering strategies.