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Authors
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Hejazi, I. ; Seyfi, J. ; Hejazi, E. ; Sadeghi, G.M.M. ; Jafari, S.H. ; Khonakdar, H. A.
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Title
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Investigating the role of surface micro/Nano structure in cell adhesion behavior of superhydrophobic polypropylene/nanosilica surfaces
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Date
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01.03.2015
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Number
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47085
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Abstract
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The main aim of the current study was to investigate the effects of different topographical features on the biological performance of polypropylene (PP)/silica coatings. To this end, a novel method including combined use of nanoparticles and non-solvent was used for preparation of superhydrophobic PP coatings. The proposed method led to a much more homogeneous appearance with a better adhesion to the glass substrate. Moreover, a notable reduction was observed in the required contents of nanoparticles (100–20 wt% with respect to the polymer) and non-solvent (35.5–9 vol%) for achieving superhydrophobicity. Surface composition and morphology of the coatings were also investigated via X-ray photoelectron spectroscopy and scanning electron microscopy. Based on both qualitative and quantitative evaluations, it was found that the superhydrophobic coatings with only nano-scale roughness strongly prevented adhesion and proliferation of 4T1 mouse mammary tumor cells as compared to the superhydrophobic surfaces with micro-scale structure. Such results demonstrate that the cell behavior could be controlled onto the polymer and nanocomposite-based surfaces via tuning the surface micro/nano structure.
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Publisher
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Colloids and Surfaces B: Biointerfaces
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Wikidata
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Citation
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Colloids and Surfaces B: Biointerfaces 127 (2015) 233-240
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DOI
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https://doi.org/10.1016/j.colsurfb.2015.01.054
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Tags
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superhydrophobic cell adhesion micro/nano structure nanosilica non-solvent
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