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Authors
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Xie, D. ; Wan, G. ; Maitz, M.F. ; Lei, Y. ; Huang, N. ; Sun, H.
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Title
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Characterization and mechanical investigation of Ti-O2-x film prepared by plasma immersion ion implantation and deposition for cardiovascular stents surface modification
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Date
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13.12.2012
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Abstract
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Up to date, materials for cardiovascular stents are still far from satisfactory because of high risk of biomaterials-associated restenosis and thrombosis. Extensive efforts have been made to improve the biocompatibility of the materials by various surface modification techniques. TiO2-x films prepared by plasma immersion ion implantation and deposition (PIII&D) have shown good blood compatibility. For clinical application, surface quality and mechanical durability of the TiO2-x film on stents are also of critical importance for the long-term serving. In this paper we present our research results on surface quality, mechanical investigation and characterization of TiO2-x films prepared using PIII&D on stent products provided by Boston Scientific SCIMED. TiO2-x films with mostly Rutile and little non-stoichiometric phases were obtained with smoothness of <3 nm RMS, largely homogeneity as well as good intergradient film/substrate interface. The TiO2-x films on stents products were sustained balloon-expansion of clinically-required extent without mechanical failure, showing highly potential feasibility for cardiovascular stents application.
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Journal
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Nuclear Instruments and Methods in Physics Research B 289 (2012) 91-96
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DOI
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https://doi.org/10.1016/j.nimb.2012.07.033
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