|
Authors
|
Zschoche, St. ; Rueda, J.C. ; Boyko, V. ; Krahl, F. ; Arndt, K.-F. ; Voit, B.
|
|
Title
|
Thermo-responsive nanogels based on poly(NiPAAm-graft-2-alkyl-2-oxazolines) crosslinked in the micellar state
|
|
Date
|
31.05.2010
|
|
Number
|
21706
|
|
Abstract
|
Graft copolymers with thermo-sensitive PNIPAAm backbone and hydrophilic PEtOxa graft chains demonstrated typical amphiphilic behavior. For specific compositions stable micelle-like aggregates were formed depending on the temperature. Applying long polyoxazoline side chains ( > 120), stable reversible micelle-like aggregates with hydrodynamic radii of 30-40 nm could be obtained between 33 and 55 °C. These graft copolymers have been successfully crosslinked by electron-beam irradiation in the micellar state yielding core/shell type nanogels with thermo-reversible swelling behavior. The temperature dependent volume change of the new thermo-responsive nanogels due to the phase transition of the PNIPAAm core has been verified by DLS.
|
|
Publisher
|
Macromolecular Chemistry and Physics
|
|
Wikidata
|
|
|
Citation
|
Macromolecular Chemistry and Physics 211 (2010) 1035-1042
|
|
DOI
|
https://doi.org/10.1002/macp.200900559
|
|
Tags
|
crosslinking electron beam irradiation graft copolymers self-organization stimuli-sensitive polymers poly-n-isopropylacrylamide block-copolymer microgels core-shell microgels drug-delivery poly(ethylene glycol) aqueous-solutions temperature poly(n-isoprop
|
