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Authors Scheler, U.
Title Electrophoretic NMR
Encyclopedia of Magnetic Resonance
Date 15.03.2012
Number 29342
Abstract Electrophoresis NMR or electrophoretic NMR is the application of pulsed field gradient NMR to the investigation of electrophoretic motion of charged moieties in solution, including ions, molecules, vesicles, and complexes. The application of a strong electric field requires a dedicated NMR probehead. Designs of increasing complexity are discussed, with respect to sensitivity and to the resolution of the sign of the electrophoretic mobility. Dedicated data processing results in two-dimensional phase-sensitive spectra correlating chemical shift that identifies the moving species with the electrophoretic mobility. Applications include the investigation of ion mobilities, the separation of spectra in mixtures, and the study of complexes. Combining electrophoretic results with the hydrodynamic friction determined from a diffusion experiment, the effective charges of molecules and complexes can be determined, allowing insight into counterion condensation.
Publisher Wiley & Sons, Ltd.
Wikidata
Citation Wiley & Sons, Ltd. (2012) 7 Seiten
DOI https://doi.org/10.1002/9780470034590.emrstm0154.pub2
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