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Dr. Mikhail Tsurkan

Institute of Biofunctional Polymer Materials
+49 351 4658 1265 +49 351 4658 533

Mikhail Tsurkan PhD is the leader of the spin-off project TissueGUARD. The project TissueGUARD is part of the EXIST program and is funded by the German Federal Ministry for Economic Affairs and Energy (BMWi) and the European Social Fund (ESF) as well as the Leibniz Institute of Polymer Research Dresden (IPF) Germany.

Fields of work

The research is focused on the development of new Biofunctional Materials for the needs of regenerative therapies and stem cell research which includes:

  • Design and synthesis of peptide and carbohydrate conjugates for biomedical and biomaterial applications
  • Incorporation of biological active molecules into hydrogel materials through rational synthesis
  • Photochemical and photophysical developments for biofunctional materials applications
  • Development of bioanalytical methods for natural compounds and biopolymers characterization

Additional information

Publications

  • Klinger, Ch. ; Zoltowska-Aksamitowska, S. ; Wysokowski, M. ; Tsurkan, M. ; Galli, R. ; et al., Express method for isolation of ready-to-use 3D chitin scaffolds from aplysina archeri (aplysineidae: verongiida) demosponge more Marine Drugs 17 (2019) ID 131
  • Shaala, L. A. ; Asfour, H.Z. ; Youssef, D.T.A. ; Zoltowska-Aksamitowska, S. ; Wysokowski, M. ; Tsurkan, M. ; et al., New source of 3D chitin scaffolds: The red sea demosponge pseudoceratina arabica (pseudoceratinidae, verongiida) more Marine Drugs 17 (2019) ID 92
  • Rahman, M. ; Mukherjee, A. ; Kovalev, I. ; Kopchuk, D. ; Zyryanov, G. ; Tsurkan, M. ; Majee, A. ; Ranu, B. ; Charishin, V.N. ; Chupakhin, O. ; Santra, S. Recent advances on diverse decarboxylative reactions of amino acids more Advanced Synthesis & Catalysis 361 (2018) Accepted article
  • Atallah, P. ; Schirmer, L. ; Tsurkan, M. ; Limasale, Y. D. P. ; Zimmermann, R. ; Werner, C. ; Freudenberg, U. In situ-forming, cell-instructive hydrogels based on glycosaminoglycans with varied sulfation patterns more Biomaterials 181 (2018) 227-239
  • Zóltowska-Aksamitowska, S. ; Tsurkan, M. ; Lim, S. C. ; et al., The demosponge Pseudoceratina purpurea as a new source of fibrous chitin more International Journal of Biological Macromolecules 112 (2018) 1021-1028
  • Vogler, S. ; Prokoph, S. ; Freudenberg, U. ; Binner, M. ; Tsurkan, M. ; Werner, C. ; Kempermann, G. Defined geldrop cultures maintain neural precursor cells more Scientific Reports 8 (2018) ID8433
  • Ehrlich, H. ; Shaala, L. A. ; Tsurkan, M. ; et al., Discovery of chitin in skeletons of non-verongiid Red Sea demosponges more PLoS ONE 13 (2018) e0195803
  • Zoltowska-Aksamitowska, S. ; Shaala, L. A. ; Tsurkan, M. ; et al., First Report on Chitin in a Non-Verongiid Marine Demosponge: The Mycale euplectellioides Case more Marine Drugs 16 (2018) ID68
  • Ehrlich, H. ; Bazhenov, V. V. ; Debitus, C. ; de Voogd, N. ; Galli, R. ; Tsurkan, M. ; Wysokowski, M. ; Meißner, H. ; Bulut, E. ; Kaya, M. ; Jesionowski, T. Isolation and identification of chitin from heavy mineralized skeleton of Suberea clavata (Verongida: Demospongiae: Porifera) marine demosponge more International Journal of Biological Macromolecules 104 (2017) 1706-1712
  • Gvaramia, D. ; Müller, E. ; Müller, K. ; Atallah, P. ; Tsurkan, M. ; Freudenberg, U. ; Bornhäuser, M. ; Werner, C. Combined influence of biophysical and biochemical cues on maintenance and proliferation of hematopoietic stem cells more Biomaterials 138 (2017) 108-117
  • Maitz, M.F. ; Zitzmann, J. ; Hanke, J. ; Renneberg, C. ; Tsurkan, M. ; Sperling, C. ; Freudenberg, U. ; Werner, C. Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors more Biomaterials 135 (2017) 53-61
  • Weber, H. ; Tsurkan, M. ; Magno, V. ; Freudenberg, U. ; Werner, C. Heparin-based hydrogels induce human renal tubulogenesis in vitro more Acta Biomaterialia 57 (2017) 59-69
  • Tsurkan, M. ; Jungnickel, C. ; Schlierf, M. ; Werner, C. Forbidden chemistry: Two-photon pathway in [2+2] cycloaddition of maleimides more Journal of the American Chemical Society 139 (2017) 10184-10187
  • Magno, V. ; Friedrichs, J. ; Weber, H. ; Prewitz, M. ; Tsurkan, M. ; Werner, C. Macromolecular crowding for tailoring tissue-derived fibrillated matrices more Acta Biomaterialia 55 (2017) 109-119
  • Binner, M. ; Bray, L. ; Friedrichs, J. ; Tsurkan, M. ; Werner, C. Cell-instructive starPEG-heparin-collagen composite matrices more Acta Biomaterialia 53 (2017) 70-80
  • Jungnickel, C. ; Tsurkan, M. ; Eogan, K. ; Werner, C. ; Schlierf, M. Bottom-Up structuring and site-selective modification of hydrogels using a two-photon [2+2] cycloaddition of maleimide more Advanced Materials 29 (2017) Art.No. 1603327
  • Nowak, M. ; Freudenberg, U. ; Tsurkan, M. ; Werner, C. ; Levental, K. Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro more Biomaterials 112 (2017) 20-30
  • Seib, P. ; Tsurkan, M. ; Freudenberg, U. ; Kaplan, D. L. ; Werner, C. Heparin-modified polyethylene glycol microparticle aggregates for focal cancer chemotherapy more ACS Biomaterials Science & Engineering 2 (2016) 2287-2293
  • Ehrlich, H. ; Maldonado, M. ; Tsurkan, M. ; ..., ; u.a., Supercontinuum generation in naturally occurring glass sponges spicules more Advanced Optical Materials 4 (2016) 1608-1613
  • Ehrlich, H. ; Motylenko, M. ; Tsurkan, M. ; et al., Multiphase biomineralization: Enigmatic invasive siliceous diatoms produce crystalline calcite more Advanced Functional Materials 26 (2016) 2503-2510
  • Freudenberg, U. ; Zieris, A. ; Chwalek, K. ; Tsurkan, M. ; Maitz, M.F. ; Atallah, P. ; Levental, K. ; Eming, S. A. ; Werner, C. Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds more Journal of Controlled Release 220 (2015) 79-88
  • Newland, B. ; Welzel, P. ; Newland, H. ; Renneberg, C. ; Kolar, P. ; Tsurkan, M. ; Rosser, A. ; Freudenberg, U. ; Werner, C. Tackling cell transplantation anoikis: An injectable, shape memory cryogel microcarrier platform material for stem cell and neuronal cell growth more Small 11 (2015) 5047-5053
  • Wysokowski, M. ; Motylenko, M. ; Beyer, J. ; ..., ; Tsurkan, M. Extrem biomimetic approach for developing novel chitin-GeO2 nanocomposites with photoluminescent properties more Nano Research 8 (2015) 2288-2301
  • Tsurkan, M. ; Wetzel, R. ; Pérez-Hernández, H. ; Chwalek, K. ; Kozlova, A. ; Freudenberg, U. ; Kempermann, G. ; Zhang, Y. ; Lasagni, A. ; Werner, C. Photopatterning of multifunctional hydrogels to direct adult neural precursor cells more Advanced Healthcare Materials 4 (2015) 516-521
  • Thompson, M. ; Tsurkan, M. ; Chwalek, K. ; Bornhäuser, M. ; Schlierf, M. ; Werner, C. ; Zhang, Y. Self-assembling hydrogels crosslinked solely by receptor-ligand interactions: Tunability, rationalization of physical properties and 3D cell culture more Chemistry - A European Journal 21 (2015) 3178-3182