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Dr. Manfred Maitz

Institute of Biofunctional Polymer Materials
+49 351 4658 606/ 313 +49 351 4658 533

Personal Data

Manfred Maitz is responsible for the field of hemocompatible surfaces in the Institute Biofunctional Polymer Materials. He is a medical doctor (Dr. med.) by education and has been working on biomaterials research in institutes in Würzburg, Ulm, Magdeburg, Dresden and Chengdu (PR China) before he joined the IPF in 2006.

He is appointed Guest Professor at Southwest Jiaotong University, School of Materials Science and Engineering in Chengdu, where he has annual research stays as guest scientist.

His focus of research is on feedback responsive materials to control blood coagulation and inflammatory responses at biomaterials in blood. These are important as vascular stents, artificial heart valves, hemodialysis membranes or tubings for extracorporeal circulation, etc.

 Research experiences

2006 – presentResearch Fellow and Group Leader, Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials Dresden, Germany
2005Foreign Expert scientist, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China
2000 – 2004Thematic field leader, Research Center Rossendorf, Institute of Ion Beam Physics and Materials Research, Dresden, Germany
1999Assistant, Institute for Pathology, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany
1998Research Fellow, Central Institute of Biomedical Techniques, University of Ulm, Ulm, Germany

 Membership of Academic Societies

Profiles

Key Publications

  1. Maitz M.F., Zitzmann J., Hanke J., Renneberg C., Tsurkan M.V., Sperling C., Freudenberg U., Werner C. Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors. Biomaterials 135: 53-61 (2017). doi:10.1016/j.biomaterials.2017.04.044
  2. Herklotz M., Hanke J., Hänsel S., Drichel J., Marx M., Maitz M.F., Werner C. Biomaterials trigger endothelial cell activation in co-incubation with human whole blood. Biomaterials 104: 258-268 (2016). doi:10.1016/j.biomaterials.2016.07.022
  3. Maitz M.F. Applications of synthetic polymers in clinical medicine. Biosurf Biotribol 1(3): 161-176 (2015). doi:10.1016/j.bsbt.2015.08.002
  4. http://dx.doi.org/10.1016/j.bsbt.2015.08.002Maitz M.F., Freudenberg U., Tsurkan M.V., Fischer M., Beyrich T., Werner C. Bio-responsive polymer hydrogels homeostatically regulate blood coagulation. Nature Commun (2013). doi:10.1038/ncomms3168
  5. Sperling C., Fischer M., Maitz M.F., Werner C. Blood coagulation on biomaterials requires the combination of distinct activation processes. Biomaterials 30(27): 4447-4456 (2009). doi:10.1016/j.biomaterials.2009.05.044
  6. Werner C., Maitz M.F., Sperling C. Current strategies towards hemocompatible coatings. J Mater Chem 17: 3376-3384 (2007). doi:10.1039/b703416b

 

Publications

  • Qiu, H. ; Qi, P. ; Liu, J. ; Yang, Y. ; Tan, X. ; Xiao, Y. ; Maitz, M.F. ; Huang, N. ; Yang, Z. Biomimetic engineering endothelium-like coating on cardiovascular stent through heparin and nitric oxide-generating compound synergistic modification strategy more Biomaterials 207 (2019) 10-22
  • Tu, Q. ; Shen, X. ; Liu, Y. ; Zhang, Q. ; Zhao, X. ; Maitz, M.F. ; Liu, T. ; Quiu, H. ; Wang, J. ; Huang, N. ; Yang, Z. A facile metal-phenolic-amine strategy for dual-functionalization of blood-contacting devices with antibacterial and anticoagulant properties more Materials Chemistry Frontiers 3 (2019) 265-275
  • Li, X. ; Gao, P. ; Tan, J. ; Xiong, K. ; Maitz, M.F. ; Pan, C. ; Wu, H. ; Chen, Y. ; Yang, Z. ; Huang, N. Assembly of metal-phenolic/catecholamine networks for synergistically anti-inflammatory, antimicrobial, and anticoagulant coatings more ACS Applied Materials & Interfaces 10 (2018) 40844-40853
  • Li, P. ; Zhou, N. ; Qiu, H. ; Maitz, M.F. ; Wang, J. ; Huang, N. In vitro and in vivo cytocompatibility evaluation of biodegradable magnesium-based stents: a review more Science China Materials 61 (2018) 501-515
  • Yang, Y. ; Li, X. ; Qiu, H. ; Li, P. ; Qi, P. ; Maitz, M.F. ; You, T. ; Yang, Z. ; Tian, W. ; Huang, N. Polydopamine modified TiO2 nanotube arrays for long-term controlled elution of bivalirudin and improved hemocompatibility more ACS Applied Materials & Interfaces 10 (2018) 7649-7660
  • Schulz, S. ; Maitz, M.F. ; Hansel, S. ; Renner, L. ; Werner, C. Analyzing the antiseptic capacity of silver-functionalized poly(ethylene glycol)-heparin hydrogels after human whole blood exposure more Biomaterials Science 6 (2018) 1129-1139
  • El-Hossary, F. M. ; El-Rahman, A. M. ; Qu, S. X. ; Zhao, J. S. ; Maitz, M.F. ; EL-Kassem, M. A. Effect of DC-pulsed magnetron sputtering power on structural, tribological and biocompatibility of Ti-Zr-N thin film more Applied Physics / A 124 (2018) ID42
  • Maitz, M.F. ; Sperling, C. ; Wongpinyochit, T. ; Herklotz, M. ; Werner, C. ; Seib, P. Biocompatibility assessment of silk nanoparticles: hemocompatibility and internalization by human blood cells more Nanomedicine: Nanotechnology, Biology and Medicine 13 (2017) 2633-2642
  • Fischer, M. ; Maitz, M.F. ; Werner, C. Coatings for biomaterials to improve hemocompatibility more Woodhead Publishing 1 (2017) Chap. 9
  • Sperling, C. ; Maitz, M.F. ; Werner, C. Test methods for hemocompatibility of biomaterials more Woodhead Publishing 1 (2017) 77-104
  • Braune, S. ; Sperling, C. ; Maitz, M.F. ; Steinseifer, U. ; Clauser, J. ; Krajewski, S. ; Wendel, H. P. ; Jung, F. Evaluation of platelet adhesion and activation on polymers: Round-robin study to assess inter-center variability more Colloids and Surfaces B: Biointerfaces 158 (2017) 416-422
  • Maitz, M.F. ; Zitzmann, J. ; Hanke, J. ; Renneberg, C. ; Tsurkan, M. ; Sperling, C. ; Freudenberg, U. ; Werner, C. Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors more Biomaterials 135 (2017) 53-61
  • Sperling, C. ; Fischer, M. ; Maitz, M.F. ; Werner, C. Neutrophil extracellular trap formation upon exposure of hydrophobic materials to human whole blood causes thrombogenic reactions more Biomaterials Science 5 (2017) 1998-2008
  • Chen, Y. ; Zhang, X. ; Zhao, S. ; Maitz, M.F. ; Zhang, W. ; Yang, S. ; Mao, J. ; Huang, N. ; Wan, G. In situ incorporation of heparin/bivalirudin into a phytic acid coating on biodegradable magnesium with improved anticorrosion and biocompatible properties more Journal of Materials Chemistry B 5 (2017) 4162-4176
  • Wang, J. ; Liu, L. ; Wu, Y. ; Maitz, M.F. ; Wang, Z. ; Koo, Y. ; Zhao, A. S. ; Sankar, J. ; Kong, D. ; Huang, N. ; Yun, Y. Ex vivo blood vessel bioreactor for analysis of the biodegradation of magnesium stent models with and without vessel wall integration more Acta Biomaterialia 50 (2017) 546-555
  • Chen, J. ; Li, Q. ; Li, J. ; Maitz, M.F. The effect of anti-CD34 antibody orientation control on endothelial progenitor cell capturing cardiovascular devices more Journal of Bioactive and Compatible Polymers 31 (2016) 583-599
  • Herklotz, M. ; Hanke, J. ; Hänsel, S. ; Drichel, J. ; Marx, M. ; Maitz, M.F. ; Werner, C. Biomaterials trigger endothelial cell activation when co-incubated with human whole blood more Biomaterials 104 (2016) 258-268
  • Chen, Y. ; Zhang, W. ; Maitz, M.F. ; Chen, M. ; Zhang, H. ; Mao, J. ; Zhao, Y. ; Huang, N. ; Wan, G. Comparative corrosion behavior of Zn with Fe and Mg in the course of immersion degradation in phosphate buffered saline more Corrosion Science 111 (2016) 541-555
  • Ye, C. ; Wang, Y. ; Su, H. ; Yang, P. ; Huang, N. ; Maitz, M.F. ; Zhao, A. S. Construction of a fucoidan/laminin functional multilayer to direction vascular cell fate and promotion hemocompatibility more Materials Science and Engineering C 64 (2016) 236-242
  • Luo, R. ; Wang, X. ; Deng, J. ; Zhang, H. ; Maitz, M.F. ; Yang, L. ; Wang, J. ; Huang, N. ; Wang, Y. Dopamine-assisted deposition of poly(ethylene imine) for efficient heparinization more Colloids and Surfaces B: Biointerfaces 144 (2016) 90-98
  • Chen, Z. ; Li, Q. ; Chen, J. ; Luo, R. ; Maitz, M.F. ; Huang, N. Immobilization of serum albumin and peptide aptamer for EPC on polydopamine coated titanium surface for enhanced in-situ self-endothelialization more Materials Science and Engineering C 60 (2016) 219-229
  • Zhou, F. ; Cui, Y. Y. ; Wu, L. L. ; Yang, J. ; Liu, L. ; Maitz, M.F. ; Brown, I. G. ; Huang, N. Ananlysis of flow field in mechanical aortic bileaflet heart valves using finite volime method more Journal of Medical and biological Engineering 36 (2016) 110-120
  • Chen, J. ; Huang, N. ; Li, Q. ; Chu, C. H. ; Li, J. ; Maitz, M.F. The effect of electrostatic heparin/collagen layer-by-layer coating degradation on the biocompatibility more Applied Surface Science 362 (2016) 281-289
  • Freudenberg, U. ; Zieris, A. ; Chwalek, K. ; Tsurkan, M. ; Maitz, M.F. ; Atallah, P. ; Levental, K. ; Eming, S. A. ; Werner, C. Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds more Journal of Controlled Release 220 (2015) 79-88
  • Chen, S. ; Zhang, J. ; Chen, Y. ; Zhao, S. ; Chen, M. ; Li, X. ; Maitz, M.F. ; Wang, J. ; Huang, N. Application of phenol/amine copolymerized film modified magnesium alloys: anticorrosion and surface biofunctionalization more ACS Applied Materials & Interfaces 7 (2015) 24510-24522