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Authors Freudenberg, U. ; Atallah, P. ; Limasale, Y. D. P. ; Werner, C.
Title Charge-tuning of glycosaminoglycan-based hydrogels to program cytokine sequestration
Date 22.02.2019
Number 56461
Abstract Glycosaminoglycan(GAG)-based biohybrid hydrogels of varied GAG content and GAG sulfation pattern were prepared and applied to sequester cytokines. The binding of strongly anionic and cationic cytokines correlated with the integral space charge density of the hydrogel while the binding of weakly charged cytokines was governed by the GAG sulfation pattern.
Publisher Faraday Discussions
Wikidata
Citation Faraday Discussions 219 (2019) 244-251
DOI https://doi.org/10.1039/C9FD00016J
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