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Authors Wojciechowska, D. ; Herczynska, L. ; Simon, F. ; Puchalski, M. ; Stawski, D.
Title Antioxidant and hydrophilic poly(lactic acid) fibers obtained through their modification with amines and ferulic acid
Date 15.09.2017
Number 53281
Abstract The ferulic acid (FA) is a natural antioxidant, abundantly present in plants, which acts as the plants immune system. In order to take advantage of its properties, a method has been developed, which combines antioxidant FA with bio-based biodegradable poly(lactic acid) fibers and biocompatible hydrophilic polyallylamine, enabling the production of versatile base material that could be used for active anti-inflammatory wound dressings. The fibers are first subjected to aminolysis in order to obtain amino moieties on the surface, able to react with the molecules of FA. Next, the FA was attached to the aminolyzed fibers surface with use of 1-ethyl-3–(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide. The anti-inflammatory properties of the modified fibers were assessed using 2,2-diphenyl-1-picrylhydrazyl radical scavenging assay. Presence of FA on the fibers’ surface was investigated through X-ray photoelectron spectroscopy analysis and Folin–Ciocalteu (total phenolic content) test. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45112.
Publisher Journal of Applied Polymer Science
Wikidata
Citation Journal of Applied Polymer Science 134 (2017) ID52112
DOI https://doi.org/10.1002/app.45112
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