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Authors Bonadies, I. ; Longo, A. ; Androsch, R. ; Jehnichen, D. ; Göbel, M. ; Di Lorenzo, M.L.
Title Biodegradable electrospun PLLA fibers containing the mosquito-repellent DEET
Date 26.04.2019
Number 56558
Abstract The manuscript details the first literature example of fibers of poly(l-lactic acid) (PLLA) containing a mosquito repellent agent, N,N-diethyl-3-methylbenzamide (DEET). The fibers were prepared by electrospinning, are defect-free and have uniform diameter of the order of magnitude of 1·µm. Thermogravimetry and infrared spectroscopy showed that it is possible to incorporate more than 50·wt% of DEET, which is then slowly released to the environment. As such, the fibers can function as a drug delivery device. Further structural analyses disclosed that PLLA in DEET-containing fibers is semicrystalline, and contains a-crystals formed during electrospinning. Thermal, morphological and structural characterization revealed that the PLLA/DEET electrospun fibers have potential as novel material for controlled release of DEET, which, coupled with the ease of fabrication, detailed here, can provide innovative tools for fighting mosquito-caused diseases.
Publisher European Polymer Journal
Wikidata
Citation European Polymer Journal 113 (2019) 377-384
DOI https://doi.org/10.1016/J.EURPOLYMJ.2019.02.001
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