Authors
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Huang, X. ; Hauptmann, N. ; Appelhans, D. ; Formanek, P. ; Frank, S. ; Kaskel, S. ; Voit, B.
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Title
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Synthesis of hetero-polymer functionalized nanocarriers by combining surface-initiated ATRP and RAFT polymerization
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Date
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07.12.2012
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Number
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32569
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Abstract
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Smart nanocarriers are created based on a bi-functional hetero-initiator for RAFT and ATRP technique, bi-functionalizing mesoporous silica nanoparticles with two polymer types. The pH-dependent behavior of PDEAEMA as the gatekeeper polymer is verified by electrokinetic measurements and a controlled release behavior is demonstrated using doxorubicin as the drug.
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Publisher
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Small
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Wikidata
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Citation
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Small 8 (2012) 3579.3583
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DOI
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https://doi.org/10.1002/smll.201201397
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Tags
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raft atrp nanocarriers mesoporous silica nanoparticles bi-functionalization mesoporous silica nanoparticles transfer radical polymerization responsive controlled-release controlled drug-delivery nanocontainers particles biodistribution therapy system
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