Authors
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Lederer, A. ; Harnisch, C. ; Bhattacharyya, A.R. ; Fakirov, S.
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Title
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Organic solvent traces in fibrillar scaffolds for tissue engineering
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Date
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09.11.2010
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Number
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25862
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Abstract
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In the present study the amount of xylene remaining in fibrillar scaffolds after their manufacture has been estimated by means of Gas Chromatrography coupled to Mass Spectrometry (GC-MS). For this purpose model scaffolds of poly(ethylene terephthalate) (PET) comprised of microfibrils with diameters of ~1 µm or nanofibrils with diameters of 50-150 nm as well as microfibrillar scaffolds of poly(glycolic acid) (PGA) have been used. An extremely low initial amount of xylene has been found (< 20 ppm). The xylene amount dropped below 2 ppm after drying for 24 h in a vacuum at 80°C. The microfibrillar PGA scaffolds, initially containing more xylene (23.4 ppm), retained only 3.6 ppm after drying for 24 h. After drying for 48 h the amount of xylene in all the scaffolds studied reached the detection limits of the GC-MS apparatus (< 0.5 ppm).
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Publisher
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Journal of Biomimetics, Biomaterials and Tissue Engineering
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Wikidata
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Citation
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Journal of Biomimetics, Biomaterials and Tissue Engineering 7 (2010) 1-6
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DOI
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https://doi.org/www.scientific.net/JBBTE.7.1
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Tags
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