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Publications

  • Zambrano, A. ; Fracasso, G. ; Gao, M. ; Ugrinic, M. ; Wang, D. ; Appelhans, D. ; deMello, A. ; Tang, T.Y.D. Programmable synthetic cell networks regulated by tuneable reaction rates more Nature Communications 13 (2022) Article Number: 3885
  • Chalubinski, M. ; Szulc, A. ; Gorzelak-Pabis, P. ; Wojdan, K. ; Appelhans, D. ; Bryszewska, M. ; Broncel, M. The effect of maltose modified fourth generation poly(propylene imine) (PPI G4) dendrimers on the barrier functions and inflammatory activation of human vascular endothelium - Possible consequences for the medical application more Vascular Pharmacology 143 (2022) 106972
  • Jugel, W. ; Tietze, S. ; Daeg, J. ; Appelhans, D. ; Broghammer, F. ; Aigner, A. ; Karimov, M. ; Schackert, G. ; Temme, A. Targeted transposition of minicircle DNA using single-chain antibody conjugated cyclodextrin-modified poly (propylene imine) nanocarriers more Cancers 14 (2022) Article Number: 1925
  • Tassinari, S. ; Moreno, S. ; Komber, H. ; Carloni, R. ; Cangiotti, M. ; Ottaviani, M. F. ; Appelhans, D. Synthesis and biological and physico-chemical characterization of glycodendrimers and oligopeptides for the treatment of systemic lupus erythematosus more Nanoscale 14 (2022) 4654-4670
  • Jiao, C. ; Obst, F. ; Geisler, M. ; Che, Y. ; Richter, A. ; Appelhans, D. ; Gaitzsch, J. ; Voit, B. Reversible protein capture and release by redox-responsive hydrogel in microfluidics more Polymers 14 (2022) 267
  • Liubimtsev, N. ; Kösterke, T. ; Che, Y. ; Appelhans, D. ; Gaitzsch, J. ; Voit, B. Redox-sensitive ferrocene functionalised double cross-linked supramolecuar hydrogels more Polymer Chemistry 13 (2022) 427-438
  • Karimov, M. ; Appelhans, D. ; Ewe, A. ; Aigner, A. An efficient nanoscale delivery system for therapeutic nucleic acids, based on the combination of disulfide crosslinking and tyrosine-modification of polyethylenimine (PEI) more Naunyn-Schmiedeberg's Archives of Pharmacology 394 (2021) S49-S49
  • Wen, P. ; Wang, X. ; Chen, H. ; Appelhans, D. ; Liu, X. ; Wang, L. ; Huang, X. A pH self-monitoring heterogeneous multicompartmental proteinosome with spatiotemporal regulation of insulin transportation more Chinese Journal of Chemistry 39 (2021) 3386-3392
  • Jatczak-Pawlik, I. ; Gorzkiewicz, M. ; Studzian, M. ; Zinke, R. ; Appelhans, D. ; Klajnert-Maculewicz, B. ; Pulaski, L. Nanoparticles for directed immunomodulation: mannose-functionalized glycodendrimers induce interleukin-8 in myeloid cell lines more Biomacromolecules 22 (2021) 3396-3407
  • Obst, F. ; Mertz, M. ; Mehner, P. J. ; Beck, A. ; Castiglione, K. ; Richter, A. ; Voit, B. ; Appelhans, D. Enzymatic synthesis of sialic acids in microfluidics to overcome cross-inhibitions and substrate supply limitations more ACS Applied Materials & Interfaces 13 (2021) 49433-49444
  • Moreno, S. ; Boye, S. ; Al Ajeilat, H. G. ; Michen, S. ; Tietze, S. ; Voit, B. ; Lederer, A. ; Temme, A. ; Appelhans, D. Multivalent protein-loaded pH-stable polymersomes: first step toward protein targeted therapeutics more Macromolecular Bioscience 21 (2021) 2100102
  • Wehr, R. ; dos Santos, E. C. ; Muthwill, M. ; Chimisso, V. ; Gaitzsch, J. ; Meier, W. Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles more Polymer Chemistry 12 (2021) 5377-5389
  • Benseny-Cases, N. ; Álvarez-Marimon, E. ; Aso, E. ; Carmona, M. ; Klementieva, O. ; Appelhans, D. ; Ferrer, I. ; Caldera , J. In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimers disease transgenic mice using synchrotron-based infrared imaging more Scientific Reports 11 (2021) 18368
  • Jugel, W. ; Aigner, A. ; Michen, S. ; Hagstotz, A. ; Ewe, A. ; Appelhans, D. ; Schackert, G. ; Temme, A. ; Tietze, S. Targeted RNAi of BIRC5/survivin using antibody-conjugated poly(propylene imine)-based polyplexes inhibits growth of PSCA-positive tumors more Pharmaceutics 13 (2021) 676
  • Wang, X. ; Moreno, S. ; Boye, S. ; Wen, P. ; Zhang, K. ; Formanek, P. ; Lederer, A. ; Voit, B. ; Appelhans, D. Feedback-induced and oscillating pH regulation of a binary enzyme-polymersomes system more Chemistry of Materials 33 (2021) 6692-6700
  • Wang, D. ; Moreno, S. ; Boye, S. ; Voit, B. ; Appelhans, D. Detection of subtle extracellular glucose changes by artificial organelles in protocells more Chemical Communications 57 (2021) 8019-8022
  • Lai, T. H. ; Keperscha, B. ; Qiu, X. ; Voit, B. ; Appelhans, D. Long-term retarded release for the proteasome inhibitor bortezomib through temperature-sensitive dendritic glycopolymers as drug delivery system from calcium phosphate bone cement more Macromolecular Rapid Communications 42 (2021) 2100083
  • Johnbosco, C. ; Zschoche, St. ; Nitschke, M. ; Hahn, D. ; Werner, C. ; Maitz, M.F. Bioresponsive starPEG-heparin hydrogel coatings on vascular stents for enhanced hemocompatibility more Materials Science and Engineering: C 128 (2021) 112268
  • Geervliet, E. ; Moreno, S. ; Baiamonte, L. ; Booijink, R. ; Boye, S. ; Wang, P. ; Voit, B. ; Lederer, A. ; Appelhans, D. ; Bansal, R. Matrix metalloproteinase-1 decorated polymersomes, a surface-active extracellular matrix therapeutic, potentiates collagen degradation and attenuates early liver fibrosis more Journal of Controlled Release 332 (2021) 594-607
  • Wang, X. ; Moreno, S. ; Boye, S. ; Wang, P. ; Liu, X. ; Lederer, A. ; Voit, B. ; Appelhans, D. Artificial organelles with orthogonal-responsive membranes for protocell systems: Probing the intrinsic and sequential docking and diffusion of cargo into two coexisting avidin-polymersomes more Advanced Science (2021) Article Number: 2004263
  • Karimov, M. ; Appelhans, D. ; Ewe, A. ; Aigner, A. The combined disulfide cross-linking and tyrosine-modification of very low molecular weight linear PEI synergistically enhances transfection efficacies and improves biocompatibility more European Journal of Pharmaceutics and Biopharmaceutics 161 (2021) 56-65
  • Schmiegel, C.J. ; Berg, P. ; Obst, F. ; Schoch, R. ; Appelhans, D. ; Kuckling, D. Continuous flow synthesis of azoxybenzenes by reductive dimerization of nitrosobenzenes with gel-bound catalysts more European Journal of Organic Chemistry 2021 (2021) 1628-1636
  • Moreno, S. ; Voit, B. ; Gaitzsch, J. The chemistry of cross-linked polymeric vesicles and their functionalisation towards biocatalytic nanoreactors more Colloid and Polymer Science 299 (2021) 309-324
  • Wen, P. ; Wang, X. ; Moreno, S. ; Boye, S. ; Voigt, D. ; Voit, B. ; Huang, X. ; Appelhans, D. Construction of eukaryotic cell biomimetics: Hierarchical polymersomes-in-proteinosome multicompartment with enzymatic reactions modulated protein transportation more Small 17 (2021) 2005749
  • Binder, S. ; Zschoche, St. ; Voit, B. ; Gerlach, G. Semi-Interpenetrating Polymer Networks Based on N-isopropylacrylamide and 2-acrylamido-2-methylpropane Sulfonic Acid for Intramolecular Force-Compensated Sensors more Journal of the Electrochemical Society 167 (2021) 167521