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Authors Korn, P. ; Elschner, C. ; Schulz, M. C. ; Range, U. ; Mai, R. ; Scheler, U.
Title MRI and dental implantology: Two which do not exclude each other
Date 01.06.2015
Number 44984
Abstract Currently, histological techniques are used to analyse implant-tissue-interactions. However, these methods are destructive and time-consuming. Furthermore, they require a large number of animals as longitudinal observations in one individual are not possible. The evaluation by non-destructive imaging techniques provides the opportunity to study the osseous integration with a reduced number of animals and a decreased biological variability.<br />The present study examined the suitability of magnetic resonance imaging (MRI) to assess peri-implant bone formation exemplarily for a dental implant in a minipig model. Due to its compatibility to MR imaging polyetheretherketone (PEEK) coated with a thin layer of titanium was applied as implant material. Osseointegration was analysed within different peri-implant regions quantifying bone volume density and soft tissue content, which were assessed by MRI and histology, likewise.<br />It could be proven that the examined regions showed differences in bone formation; the region adjacent to the implant apex turned out to be the most dynamic. Both methods led to comparable results with no significant differences regarding to the assessed parameters.<br />Moreover, it was demonstrated that titanium coated PEEK showed a sufficient osseointegration and MRI provides a promising application in monitoring bone formation.
Publisher Biomaterials
Wikidata
Citation Biomaterials 53 (2015) 634-645
DOI https://doi.org/10.1016/j.biomaterials.2015.02.114
Tags dental implant polyetheretherketone coating osseointegration histology magnetic resonance imaging

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