Fields of Work
Biopolymer Fibers & Biocomposites
Facing the extremely complex biological system of human organism, the requirements for scaffold materials in regenerative medicine are enormous and tremendously challenging. Therefore the demands on scaffolds are well defined: biocompatibility, creation of a 3D-network with desired pore size and interconnectivity for directed cell growth and support of vascularization of the ingrown tissue, certain mechanical, physical and chemical properties and appropriate degradation characteristics with non-toxic residues. Textile implants are fascinating, they exhibit the desired properties and due to their high degree of design options and large surface-area-to-volume ratio provide ideal living conditions for cells.
Resorbable biopolymers, as rather new polymer class, are often limited in its applications due to their brittleness. However, fabricated into fibers by means of melt spinning the remarkable potential of PLA or PHB is evident: silk-like fibers with 20-200% elongation of break can be fabricated and further processed by means of textile processing. The thourough investigation of the above mentioned biopolymers, as fundamental units of textile implants, and the deep understandig of biopolymer-processing-structure-properties correlations are the key issues of our research.
- Melt spinning (multifilaments, hollow/profile/porous fibers)
- Mini - extrusion (monofilaments, composites)
- Mikro - extrusion (tubular structures)
- Electronbeam – induced reactive modification and sterilization of biopolymers
- Mechanical analysis and polymer analysis
- Degradable biopolymers for regenerative medical therapies: PLA, PCL, PHB
- Biocomposites with CaCO3
Scope of work
- Scaffold design based on fibers and textiles (e. g. bone, ligament or nerve regeneration)
- Fundamental understanding of the process of melt spinning of biopolymers and the resulting properties (e.g. mechanics, resorption, release kinetics, stability to sterilization)
Mar. 2012 – Sep. 2017
Dresden University of Technology/ IPF, Dresden, Germany
Tissue Engineering/ Scaffold Design
Nov. 2007 – Feb. 2012
Leibniz Institute of Polymer Research, Dresden, Germany
Research Divison Biofunctional Polymer Materials at the Max Bergmann Center of Biomaterials,
Thesis: nerve guidance channels based on PHB.
Oct. 2001 – Oct. 2007
Dresden University of Technology, Dresden, Germany
Major: Material Science;
Specialty: Functional Materials
June 2006 – Dec. 2006
Fraunhofer USA CCL / Michigan State University, Lansing, MI, USA
Thesis: Surface characterization and in vitro investigations
on diamond-like carbon coated biomedical alloys.
Oct. 2004–March 2005
Fraunhofer IFAM, Bremen, Germany
Research assistant – internship
Shaping and functional materials: Preparation and evaluation
of nano suspensions using a wet-milling procedure.