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Publikationen Dr. Appelhans

  • Wen, P. ; Wang, X. ; Chen, H. ; Appelhans, D. ; Liu, X. ; Wang, L. ; Huang, X. A pH self-monitoring heterogeneous multicompartmental proteinosome with spatiotemporal regulation of insulin transportation more Chinese Journal of Chemistry 39 (2021) 3386-3392
  • Jatczak-Pawlik, I. ; Gorzkiewicz, M. ; Studzian, M. ; Zinke, R. ; Appelhans, D. ; Klajnert-Maculewicz, B. ; Pulaski, L. Nanoparticles for directed immunomodulation: mannose-functionalized glycodendrimers induce interleukin-8 in myeloid cell lines more Biomacromolecules 22 (2021) 3396-3407
  • Obst, F. ; Mertz, M. ; Mehner, P. J. ; Beck, A. ; Castiglione, K. ; Richter, A. ; Voit, B. ; Appelhans, D. Enzymatic synthesis of sialic acids in microfluidics to overcome cross-inhibitions and substrate supply limitations more ACS Applied Materials & Interfaces 13 (2021) 49433-49444
  • Moreno, S. ; Boye, S. ; Al Ajeilat, H. G. ; Michen, S. ; Tietze, S. ; Voit, B. ; Lederer, A. ; Temme, A. ; Appelhans, D. Multivalent protein-loaded pH-stable polymersomes: first step toward protein targeted therapeutics more Macromolecular Bioscience 21 (2021) 2100102
  • Benseny-Cases, N. ; Álvarez-Marimon, E. ; Aso, E. ; Carmona, M. ; Klementieva, O. ; Appelhans, D. ; Ferrer, I. ; Caldera , J. In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimers disease transgenic mice using synchrotron-based infrared imaging more Scientific Reports 11 (2021) 18368
  • Jugel, W. ; Aigner, A. ; Michen, S. ; Hagstotz, A. ; Ewe, A. ; Appelhans, D. ; Schackert, G. ; Temme, A. ; Tietze, S. Targeted RNAi of BIRC5/survivin using antibody-conjugated poly(propylene imine)-based polyplexes inhibits growth of PSCA-positive tumors more Pharmaceutics 13 (2021) 676
  • Wang, X. ; Moreno, S. ; Boye, S. ; Wen, P. ; Zhang, K. ; Formanek, P. ; Lederer, A. ; Voit, B. ; Appelhans, D. Feedback-induced and oscillating pH regulation of a binary enzyme-polymersomes system more Chemistry of Materials 33 (2021) 6692-6700
  • Wang, D. ; Moreno, S. ; Boye, S. ; Voit, B. ; Appelhans, D. Detection of subtle extracellular glucose changes by artificial organelles in protocells more Chemical Communications 57 (2021) 8019-8022
  • Lai, T. H. ; Keperscha, B. ; Qiu, X. ; Voit, B. ; Appelhans, D. Long-term retarded release for the proteasome inhibitor bortezomib through temperature-sensitive dendritic glycopolymers as drug delivery system from calcium phosphate bone cement more Macromolecular Rapid Communications 42 (2021) 2100083
  • Geervliet, E. ; Moreno, S. ; Baiamonte, L. ; Booijink, R. ; Boye, S. ; Wang, P. ; Voit, B. ; Lederer, A. ; Appelhans, D. ; Bansal, R. Matrix metalloproteinase-1 decorated polymersomes, a surface-active extracellular matrix therapeutic, potentiates collagen degradation and attenuates early liver fibrosis more Journal of Controlled Release 332 (2021) 594-607
  • Wang, X. ; Moreno, S. ; Boye, S. ; Wang, P. ; Liu, X. ; Lederer, A. ; Voit, B. ; Appelhans, D. Artificial organelles with orthogonal-responsive membranes for protocell systems: Probing the intrinsic and sequential docking and diffusion of cargo into two coexisting avidin-polymersomes more Advanced Science (2021) Article Number: 2004263
  • Karimov, M. ; Appelhans, D. ; Ewe, A. ; Aigner, A. The combined disulfide cross-linking and tyrosine-modification of very low molecular weight linear PEI synergistically enhances transfection efficacies and improves biocompatibility more European Journal of Pharmaceutics and Biopharmaceutics 161 (2021) 56-65
  • Schmiegel, C.J. ; Berg, P. ; Obst, F. ; Schoch, R. ; Appelhans, D. ; Kuckling, D. Continuous flow synthesis of azoxybenzenes by reductive dimerization of nitrosobenzenes with gel-bound catalysts more European Journal of Organic Chemistry 2021 (2021) 1628-1636
  • Wen, P. ; Wang, X. ; Moreno, S. ; Boye, S. ; Voigt, D. ; Voit, B. ; Huang, X. ; Appelhans, D. Construction of eukaryotic cell biomimetics: Hierarchical polymersomes-in-proteinosome multicompartment with enzymatic reactions modulated protein transportation more Small 17 (2021) 2005749
  • Voit, B. ; Appelhans, D. Dendrimere - Polymere anders gedacht more GDCh - Faszination Chemie (2020) Online-Artikel
  • Franiak-Pietryga, I. ; Ziemba, B. ; Sikorska, H. ; Jander, M. ; Appelhans, D. ; Bryszewska, M. ; Borowiec, M. Neurotoxicity of poly(propylene imine) glycodendrimers more Drug and Chemistry Toxicology 45 (2022) 1484-1492
  • Moreno, S. ; Boye, S. ; Lederer, A. ; Formanek, P. ; Oertel, U. ; Falanga, A. ; Galdiero, S. ; Lecommandoux, S. ; Voit, B. ; Appelhans, D. Avidin localizations in pH-responsive polymersomes for probing the docking of biotinylated (macro)molecules in the membrane and lumen more Biomacromolecules 21 (2020) 5162-5172
  • Carone, M. ; Moreno, S. ; Cangiotti, M. ; Ottaviani, M. F. ; Wang, P. ; Carloni, R. ; Appelhans, D. DOTA glycodendrimers as Cu(II) complexing agents and their dynamic interaction characteristics toward liposomes more Langmuir 36 (2020) 12816-12829
  • Berg, P. ; Obst, F. ; Simon, D. ; Richter, A. ; Appelhans, D. ; Kuckling, D. Novel application of polymer networks carrying tertiary amines as a catalyst inside microflow reactors used for knoevenagelreactions more European Journal of Organic Chemistry 2020 (2020) 5765-5774
  • Moreno, S. ; Sharan, P. ; Engelke, J. ; Gumz, H. ; Boye, S. ; Oertel, U. ; Wang, P. ; Banerjee, S. ; Klajn, R. ; Voit, B. ; Lederer, A. ; Appelhans, D. Light-driven proton transfer for cyclic and temporal switching of enzymatic nanoreactors more Small 16 (2020) 2002135
  • Franiak-Pietryga, I. ; Ziemba, B. ; Sikorska, H. ; Jander, M. ; Kuncman, W. ; Danilewicz, M. ; Appelhans, D. ; Lewkowicz, P. ; Ostrowska, K. ; Bryszewska, M. ; Borowiec, M. Maltotriose-modified poly(propylene imine) Glycodendrimers as a potential novel platform in the treatment of chronic lymphocytic Leukemia. A proof-of-concept pilot study in the animal model of CLL more Toxicology and Applied Pharmacology 403 (2020) 115139
  • Che, Y. ; Gaitzsch, J. ; Liubimtsev, N. ; Zschoche, St. ; Bauer, T. ; Appelhans, D. ; Voit, B. Double cross-linked supramolecular hydrogels with tunable properties based on host-guest interactions more Soft Matter 16 (2020) 6733-6742
  • Beck, A. ; Obst, F. ; Busek, M. ; Grünzner, S. ; Mehner, P. J. ; Paschew, G. ; Appelhans, D. ; Voit, B. ; Richter, A. Hydrogel patterns in microfluidic devices by do-it-yourself UV-photolithography suitable for very large-scale intergration more Micromachines 11 (2020) 479
  • Obst, F. ; Beck, A. ; Bishayee, C. ; Mehner, P. J. ; Richter, A. ; Voit, B. ; Appelhans, D. Hydrogel microvalves as control elements for parallelized enzymatic cascade reactions in microfluidics more Micromachines 11 (2020) 167
  • Daeg, J. ; Xu, X. ; Zhao, L. ; Boye, S. ; Janke, A. ; Temme, A. ; Zhao, J. ; Lederer, A. ; Voit, B. ; Shi, X. ; Appelhans, D. Bivalent peptide- and chelator-containing bioconjugates as toolbox components for personalized nanomedicine more Biomacromolecules 21 (2020) 199-213