Authors
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Schmaljohann, D. ; Oswald, J. ; Jörgensen, B. ; Nitschke, M. ; Beyerlein, D. ; Werner, C.
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Title
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Thermo-Responsive Hydrogels for Controlled Cell Adhesion and Detachment
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Date
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03.11.2003
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Number
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11487
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Abstract
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The stimuli-responsive surface-immobilized hydrogels based on PNiPAAm-g-PEG or PDEAAm-g-PEG have been utilized as fast responding hydrogels, which allow to detach mouse fibroblasts from the substrate without enzymatic treatment. The surface-immobilized hydrogels were prepared by low-pressure plasma treatment of the spincoated films. The relatively large content of PEG (15 - 20 wt.-%) is attributed to support this fast detachment, which is caused by the collapse of the thermo-responsive polymer. Furthermore, the PEG allows to maintain certain hydrogel properties even above the transition temperature.<br /><br />Assembly and Applications of Soft Interfaces<br />The 226th ACS National Meeting, New York, NY, September 7-11, 2003
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Publisher
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Polymeric Materials: Science and Engineering
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Wikidata
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Citation
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Polymeric Materials: Science and Engineering 89 (2003) 255-256
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DOI
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http://oasys2.confex.com/acs/226nm/techprogram/P668106.HTM
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Tags
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MBC_Plasma
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