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Dr. Mikhail Tsurkan

Institute of Biofunctional Polymer Materials
+49 351 4658 644 +49 351 4658 533

Fields of work

The research is focused on the development of new Biofunctional Polymer Materials for growth and proliferation of stem cells which includes:

  • Design and synthesis of peptides and proteins for self assembly into biofunctional polymers
  • Incorporation of biological active molecules into PEG hydrogels through rational peptide synthesis

Publications

  • Maitz, M.F. ; Freudenberg, U. ; Tsurkan, M. ; Fischer, M. ; Beyrich, T. ; Werner, C. Bio-responsive polymer hydrogels homeostatically regulate blood coagulation more Nature Communications 4 (2013) 7 Seiten [OPEN]
  • Ehrlich, H. ; Kaluzhnaya, O. V. ; Tsurkan, M. ; Ereskovsky, A. ; Tabachnick, K. R. ; Ilan, M. ; Stelling, A. ; Galli, R. ; Petrova, O. V. ; Nekipelov, S. V. ; Sivkov, V. N. ; Vyalikh, D. V. ; Born, R. ; Behm, T. ; Ehrlich, A. ; Chernogor, L. I. ; Belikov, First report on chitinous holdfast in sponges (Porifera) more Proceedings of the Royal Society B 280 (2013) 20130339
  • Tsurkan, M. ; Chwalek, K. ; Prokoph, S. ; Zieris, A. ; Levental, K. ; Freudenberg, U. ; Werner, C. Defined polymer-peptide conjugates to form cell-instructive star PEG-heparin matrices in situ more Advanced Materials 25 (2013) 2606-2610
  • Tsurkan, M. ; Hauser, P. V. ; Zieris, A. ; Carvalhosa, R. ; Bussolati, B. ; Freudenberg, U. ; Gamussi, G. ; Werner, C. Growth factor delivery from hydrogel particle aggregates to promote tubular regeneration after acute kidney injury more Journal of Controlled Release 167 (2013) 248-255
  • Wieduwild, R. ; Tsurkan, M. ; Chwalek, K. ; Murawala, P. ; Nowak, M. ; Freudenberg, U. ; Neinhuis, C. ; Werner, C. ; Zhang, Y. Minimal peptide motif for non-covalent peptide-heparin hydrogels more Journal of the American Chemical Society 135 (2013) 2919-2922
  • Chwalek, K. ; Levental, K. ; Tsurkan, M. ; Zieris, A. ; Freudenberg, U. ; Werner, C. Two-tier hydrogel degradation to boost endothelial cell morphogenesis more Biomaterials 32 (2011) 9649-9657
  • Ehrlich, H. ; Deutzmann, R. ; Brunner, E. ; Cappellini, E. ; Koon, H. ; Solazzo, C. ; Yang, Y. ; Ashford, D. ; thomas-Oates, J. ; Lubeck, M. ; Baessmann, C. ; Langrock, T. ; Hoffmann, R. ; Wörheide, G. ; Reitner, J. ; Simon, P. ; Tsurkan, M. ; Ereskovsky, Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen more Nature Chemistry 2 (2010) 1084-1088
  • Ehrlich, H. ; Tsurkan, M. Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen more Nature Chemistry 2 (2010) 1084-1088
  • Tsurkan, M. ; Chwalek, K. ; Levental, K. ; Freudenberg, U. ; Werner, C. Modular starPEG-heparin gels with bifunctional peptide linkers more Macromolecular Rapid Communications 31 (2010) 1529-1533
  • Tsurkan, M. ; Levental, K. ; Freudenberg, U. ; Werner, C. Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties more Chemical Communications 46 (2010) 1141-1143