Stephan, H. ; Geipel, G. ; Appelhans, D. ; Bernhard, G. ; Tabuani, D. ; Komber, H. ; Voit, B.
Pegylation of 1,4,8,11-tetraazacyclotetradecane (cyclam) and its Cu(II) complexation

Two novel star-like cyclam derivatives appended with four amino groups and four PEG-arms have been synthesised. The complex formation of cyclam and the two cyclam derivatives with Cu(II) has been studied by UV–vis and time-resolved laser-induced fluorescence (TRLFS) measurements outlining 1:1 complexes between cyclam ligands and Cu(II). By TRLFS measurements a quench effect of the Cu(II) on the fluorescence of the ligand was also found to determine the complex formation between Cu(II) and the ligands.

Quelle
Tetrahedron Letters 46

Seiten
3209-3212

DOI
http://dx.doi.org/10.1016/j.tetlet.2005.03.051

Erschienen am
April 2005