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Janaszewska, A. ; Ziemba, B. ; Ciepluch, K. ; Appelhans, D. ; Voit, B. ; Klajnert, B. ; Bryszewska, M.
The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluoroscein-proofs of crossing blood-brain-barrier

Oligosaccharide-modified poly(propylene imine) dendrimers are promising candidates as drug carriers and as anti-prion agents. Here, we report the biodistribution of maltotriose-modified 4th generation poly(propylene imine) (PPI) dendrimers and their ability to cross the blood–brain–barrier that is important if these glycodendrimers are considered as potential therapeutic agents in the central nervous system (CNS).

Source
New Journal of Chemistry 35

Pages
350-353

DOI
http://dx.doi.org/10.1039/c1nj20444k

Published
February 2012
 
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Polymer Structures