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A. Vyalikh, A.U.B. Wolter, S. Hampel, D. Haase, M. Ritschel, A. Leonhardt, H.-J. Grafe, A. Taylor, K. Krämer, B. Büchner, R. Klingeler
A carbon-wrapped nanoscaled thermometer for temperature control in biological environment

Aims: A carbon-wrapped nanoscaled thermometer for a contactless temperature control in biological systems on the cellular level is presented.
Materials & methods: The thermometer is based on multiwalled carbon nanotubes (MWCNTs) filled with materials with strongly temperature-dependent nuclear magnetic resonance (NMR) parameters. The NMR frequency shift and relaxation time were measured in cuprous-iodide-filled CNTs at different temperatures.
Results: The experimental data indicate a pronounced temperature dependence of the NMR parameters, thereby realizing the nanoscaled thermometer. Conclusion: This study is a proof-of-concept that the functionalized CNTs can be used as a contactless thermometer in biomedical applications.

Quelle
Nanomedicine 3, 321-327

DOI
http://dx.doi.org/10.2217/17435889.3.3.321

Erschienen am
June 2008
 
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