• Microslit Electrokinetic Set-up
    surface adherent platelets, granulocytes and fibrin after in vitro whole blood incubation
    Human hematopoetic stem and progenitor cells cultured on decellularized extracellular matrix derived from mesenchymal stromal cells
  • SEM image of a springtail cuticle
    Whole blood is filled into incubation chamber for hemocompatibility assessment
    Murine hepatocytes in collagen gel sandwich culture
  • Scheme of a single-cell force spectroscopy experiment
    Whole blood is filled into incubation chamber for hemocompatibility assessment
    Three dimensional reconstruction of a mammary epithelial cell spheroid cultivated in an in vitro biohybrid matrix

New tools and methods are developed and imple­mented to analyze and control ionic charge, molecular transport, supramole­cular structure and bio­adhesion at solid/liquid interfaces.

ELECTROSURFACE ANALYSIS:
Ralf Zimmermann

ADHESION AT BIOINTERFACES:
Jens Friedrichs

Blood-material interactions are syste­matically explored through whole blood incubation studies that enable the development of anticoagulant coatings containing various types of natural and synthetic inhibitor molecules.

ANTICOAGULANT COATINGS:
Manfred Maitz

BLOOD ACTIVATION PROCESSES:
Claudia Sperling

Decellularized or reconstituted biopoly­mer matrices and modular, bio-functional hydrogels are designed to create cell-instructive microenvironments and morphogenetic matrices for regenerative therapies.

BIOPOLYMER MATRICES:
Marina Prewitz

BIOHYBRID HYDROGELS:
Uwe Freudenberg