Dr. Mikhail Tsurkan

Dr. Mikhail Tsurkan

Dr. Mikhail Tsurkan
Biofunctional Polymer Materials
Tel. +49(0)351 4658 644 / Fax +49(0)351 4658 533

Fields of work

The research is focused on the development of new Biofunctional Polymer Materials for growth and proliferation of stem cells which includes:

  • Design and synthesis of peptides and proteins for self assembly into biofunctional polymers
  • Incorporation of biological active molecules into PEG hydrogels through rational peptide synthesis


  1. Thompson, M.; Tsurkan, M.; Chwalek, K.; Bornhäuser, M.; Schlierf, M.; Werner, C.; Zhang, Y.
    Self-assembling hydrogels crosslinked solely by receptor-ligand interactions: Tunability, rationalization of physical properties and 3D cell culture more
    Chemistry - A European Journal 21 (2015) 3178-3182

  2. Zieris, A.; Dockhorn, R.; Röhrich, A.; Zimmermann, R.; Müller, M.; Welzel, P.; Tsurkan, M.; Sommer, J.-U.; Freudenberg, U.; Werner, C.
    Biohybrid networks of selectively desulfated glycosaminoglycans for tunable growth factor delivery more
    Biomacromolecules 15 (2014) 4439-446

  3. Tsurkan, M.; Wetzel, R.; Pérez-Hernández, H.; Chwalek, K.; Kozlova, A.; Freudenberg, U.; Kempermann, G.; Zhang, Y.; Lasagni, A.; Werner, C.
    Photopatterning of multifunctional hydrogels to direct adult neural precursor cells more
    Advanced Healthcare Materials (2014) Early view

  4. Anitha, A.; Sowmya, S.; Sudheesh Kumar, P. T.; Deepthi, S.; Chennazhi, K. P.; Ehrlich, H.; Tsurkan, M.; Jayakumar, R.
    Chitin and chitosan in selected biomedical applications more
    Progress in Polymer Science 39 (2014) 1644-1667

  5. Tsurkan, M.; Chwalek, K.; Schoder, M.; Freudenberg, U.; Werner, C.
    Chemoselective peptide functionalization of starPEG-GAG hydrogels more
    Bioconjugate Chemistry 25 (2014) 1942–1950

  6. Nickerl, J.; Tsurkan, M.; Hensel, R.; Neinhuis, C.; Werner, C.
    The multi-layered protective cuticle of Collembola: a chemical analysis more
    Journal of the Royal Society Interface 11 (2014) 20140619

  7. Chwalek, K.; Tsurkan, M.; Freudenberg, U.; Werner, C.
    Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models more
    Scientific Reports 4 (2014) Article number: 4414

  8. Ehrlich, H.; Rigby, J. K.; Botting, J.; Tsurkan, M.; Werner, C.; Schwille, P.; Petrasek, Z.; Pisera, A.; Simon, P.; Sivkov, V. N.; Vyalikh, D. V.; Molodtsov, S. L.; Kurek, D.; Kammer, M.; Hunoldt, S.; Born, R.; Stawski, D.; Steinhoff, B.; Bazhenov, V. V.; Geisler-Wierwille, T.
    Discovery of 505-million-year old chitin in the basal demosponge Vauxia gracilenta more
    Scientific Reports 3 (2013) 3497

  9. Wysokowski, M.; Bazhenov, V. V.; Tsurkan, M.; Galli, R.; Stelling, A.; Stöcker, H.; Kaiser, S.; Niederschlag, E.; Gärtner, G.; Behm, T.; Ilan, M.; Petrenko, A. Y.; Jesionowski, T.; Ehrlich, H.
    Isolation and identification of chitin in three-dimensional skeleton of aplysina fistularis marin sponge more
    International Journal of Biological Macromolecules 62 (2013) 94-100

  10. Ehrlich, H.; Kaluzhnaya, O. V.; Brunner, E.; Tsurkan, M.; Ereskovsky, A.; Ilan, M.; Tabachnick, K. R.; Bazhenov, V. V.; Paasch, S.; Kammer, M.; Born, R.; Stelling, A.; Galli, R.; Belikov, S.; Petrova, O. V.; Sivkov, V. N.; Vyalikh, D. V.; Hunoldt, S.; Wörheide, G.
    Identification and first insights into the structure and biosynthesis of chitin from the freshwater sponge Spongilla lacustris more
    Journal of Structural Biology 183 (2013) 474-483

  11. Maitz, M.F.; Freudenberg, U.; Tsurkan, M.; Fischer, M.; Beyrich, T.; Werner, C.
    Bio-responsive polymer hydrogels homeostatically regulate blood coagulation more
    Nature Communications 4 (2013) 7 Seiten [OPEN]

  12. Ehrlich, H.; Kaluzhnaya, O. V.; Tsurkan, M.; Ereskovsky, A.; Tabachnick, K. R.; Ilan, M.; Stelling, A.; Galli, R.; Petrova, O. V.; Nekipelov, S. V.; Sivkov, V. N.; Vyalikh, D. V.; Born, R.; Behm, T.; Ehrlich, A.; Chernogor, L. I.; Belikov, S.; Janussen, D.; Bazhenov, V. V.; Wörheide, G.
    First report on chitinous holdfast in sponges (Porifera) more
    Proceedings of the Royal Society B 280 (2013) 20130339

  13. Tsurkan, M.; Chwalek, K.; Prokoph, S.; Zieris, A.; Levental, K.; Freudenberg, U.; Werner, C.
    Defined polymer-peptide conjugates to form cell-instructive star PEG-heparin matrices in situ more
    Advanced Materials 25 (2013) 2606-2610

  14. Tsurkan, M.; Hauser, P. V.; Zieris, A.; Carvalhosa, R.; Bussolati, B.; Freudenberg, U.; Gamussi, G.; Werner, C.
    Growth factor delivery from hydrogel particle aggregates to promote tubular regeneration after acute kidney injury more
    Journal of Controlled Release 167 (2013) 248-255

  15. Wieduwild, R.; Tsurkan, M.; Chwalek, K.; Murawala, P.; Nowak, M.; Freudenberg, U.; Neinhuis, C.; Werner, C.; Zhang, Y.
    Minimal peptide motif for non-covalent peptide-heparin hydrogels more
    Journal of the American Chemical Society 135 (2013) 2919-2922

  16. Chwalek, K.; Levental, K.; Tsurkan, M.; Zieris, A.; Freudenberg, U.; Werner, C.
    Two-tier hydrogel degradation to boost endothelial cell morphogenesis more
    Biomaterials 32 (2011) 9649-9657

  17. Ehrlich, H.; Deutzmann, R.; Brunner, E.; Cappellini, E.; Koon, H.; Solazzo, C.; Yang, Y.; Ashford, D.; thomas-Oates, J.; Lubeck, M.; Baessmann, C.; Langrock, T.; Hoffmann, R.; Wörheide, G.; Reitner, J.; Simon, P.; Tsurkan, M.; Ereskovsky, A.; Kurek, D.; Bazhenoc, V.; Hunoldt, S.; Mertig, M.; Vyalikh, D. V.; Molodtsov, S. L.; Kummer, K.; Worch, H.; Smetacek, V.; Collins, M. J.
    Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen more
    Nature Chemistry 2 (2010) 1084-1088

  18. Ehrlich, H.; Tsurkan, M.
    Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen more
    Nature Chemistry 2 (2010) 1084-1088

  19. Tsurkan, M.; Chwalek, K.; Levental, K.; Freudenberg, U.; Werner, C.
    Modular starPEG-heparin gels with bifunctional peptide linkers more
    Macromolecular Rapid Communications 31 (2010) 1529-1533

  20. Tsurkan, M.; Levental, K.; Freudenberg, U.; Werner, C.
    Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties more
    Chemical Communications 46 (2010) 1141-1143

Dr. Mikhail Tsurkan
Dr. Mikhail Tsurkan


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Dr. Mikhail Tsurkan