Bioactive nanostructured surfaces

Based on the understanding of the adhesion mechanisms of target organisms, we develop biocide-free bioactive antifouling surfaces. For example, as many fouling species use proteins and glycoprotein polymers to attach to surfaces, we explore strategies for the use of immobilized proteolytic enzymes to prevent marine biofouling. Investigations of the impact of the characteristics of the polymer films on the amount, conformation, availability function, and release of bioactive molecules; together with studies if the influence of bioactive compounds on cell adhesion will enable the rational design of surfaces with optimal antifouling properties.

Adhesion strength of adhered spores of the green algae Ulva linza to active (A) and heat-denatured (D) coatings with increasing amount and activity of immobilized Subtilisin A. dark bars show spore density after 45 min settlement and washing, light bars after exposure to an impact pressure of 34 kPa. Work performed in collaboration with the University of Birmingham.

Relevant Publications

 
Bioactive nanostructured surfaces
Bioactive nanostructured surfaces
 

Departments

Institute of Biofunctional Polymer Materials

Fields of Work

Charging and Structure Formation at Biointerfaces

Biomimetic Antifouling

Bioactive nanostructured surfaces